Allerjik ve allerjik olmayan astımlı hastaların klinik özellikleri ve solunum fonksiyonlarının karşılaştırılması
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Tarih
2008
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info:eu-repo/semantics/openAccess
Özet
Amaç: Allerjik ve allerjik olmayan astımlı hastaların demografik ve klinik özellikleri ve solunum fonksiyon değerlerinin karşılaştırılması. Gereç ve Yöntem: Ocak 2005-Ocak 2007 tarihleri arasında Göğüs Hastalıkları Polikliniğinde astım tanısı konulan ve prik testi yapılan hastaların retrospektif olarak incelenmesi. Bulgular: Çalışmaya 233 astımlı hasta (102 allerjik, 131 allerjik olmayan) alındı. Allerjik astımlılarda allerjik olmayanlara göre 50 yaş altındaki hasta oranı daha fazla idi (Allerjiklerde %66, allerjik olmayanlarda %50, p<0.05). Hastaların 175’i (%75) kadın idi ve allerjik olmayan astımlılarda kadın hasta oranı (%82) allerjik astımlılara (%67) göre daha fazla idi (p= 0.009). Allerjik astımlılarda ortaokul ve üzeri eğitimlilerin oranı daha yüksek idi (p<0.001). Burun tıkanıklığı, burun akıntısı ve hapşırma yakınmalarının sıklığı allerjik astımlılarda (p<0.05), nefes darlığının sıklığı allerjik olmayan astımlılarda daha fazla idi (p= 0.002). Solunum fonksiyon testlerinin karşılaştırılmasında allerjik astımlıların ortalama FVC (%) ve FEV1 (%) değerleri allerjik olmayan astımlılara göre belirgin olarak daha yüksekti (p<0.001). Prik testinde en sık akarlara (79 kişide) ve polenlere (48 kişide) karşı pozitiflik saptandı. Sonuçlar: Bu çalışmada allerjik olmayan astımın ileri yaş, kadın cinsiyet, düşük eğitim seviyesi ve düşük solunum fonksiyon değerleri ile ilişkili olduğu bulundu. Burun akıntısı, burun tıkanıklığı ve hapşırma yakınmalarının allerjik astımlılarda, nefes darlığı yakınmasının ise allerjik olmayan astımlılarda daha sık olduğu saptandı. Allerjik astımlılarda saptanan en yaygın allerjiler akarlar ve polenler idi. Astımlı hastalarda altta yatan allerji varlığının erken dönemde saptanması hastaların tedavi ve izleminde önemlidir.
Aim: To compare demographic and clinical characteristics and pulmonary function values of allergic and nonallergic asthmatic patients. Material and Methods: Retrospective analysis of patients underwent skin prick test and had the diagnosis of asthma in chest disease clinic between January 2005 and January 2007. Results: Two hundred and thirty three asthmatic patients (102 allergic and 131 non-allergic) were enrolled to study. The number of allergic patients under 50 years old was more than non-allergic asthmatic patients (66% in allergic patients and 50% in non-allergic patients, p<0.05). Of the patients 175 (75%) were female and the rate of female patients in non-allergic asthmatic (82%) was more than allergic asthmatic patients (67%) (p=0.009). The rate of patients with education level of secondary school or above was higher in allergic asthmatics (p<0.001). The frequency of symptoms such as nasal obstruction, nasal discharge and sneezing was higher in allergic asthmatics (p<0.05) and frequency of dyspnea was higher in non-allergic asthmatics (p=0.002). In comparison of pulmonary function test parameters; mean FVC (%) and FEV1 (%) values were significantly higher in allergic asthmatics than non-allergic ones (p<0.001). In skin prick test most commonly encountered positive reactions were against house dust mites (79 patients) and pollens (48 patients). Conclusion: In this study, we detected that non-allergic asthma was related to older age, female gender, lower education level and lower pulmonary function test values. Nasal discharge, nasal obstruction and sneezing complaints were frequent in allergic asthmatics and dyspnea was more frequent in non-allergic asthmatics. Most common allergies in allergic asthmatics were house dust mites and pollens. Detection of presence of allergy in asthmatic patients in early period is important in treatment and follows up of patients.
Aim: To compare demographic and clinical characteristics and pulmonary function values of allergic and nonallergic asthmatic patients. Material and Methods: Retrospective analysis of patients underwent skin prick test and had the diagnosis of asthma in chest disease clinic between January 2005 and January 2007. Results: Two hundred and thirty three asthmatic patients (102 allergic and 131 non-allergic) were enrolled to study. The number of allergic patients under 50 years old was more than non-allergic asthmatic patients (66% in allergic patients and 50% in non-allergic patients, p<0.05). Of the patients 175 (75%) were female and the rate of female patients in non-allergic asthmatic (82%) was more than allergic asthmatic patients (67%) (p=0.009). The rate of patients with education level of secondary school or above was higher in allergic asthmatics (p<0.001). The frequency of symptoms such as nasal obstruction, nasal discharge and sneezing was higher in allergic asthmatics (p<0.05) and frequency of dyspnea was higher in non-allergic asthmatics (p=0.002). In comparison of pulmonary function test parameters; mean FVC (%) and FEV1 (%) values were significantly higher in allergic asthmatics than non-allergic ones (p<0.001). In skin prick test most commonly encountered positive reactions were against house dust mites (79 patients) and pollens (48 patients). Conclusion: In this study, we detected that non-allergic asthma was related to older age, female gender, lower education level and lower pulmonary function test values. Nasal discharge, nasal obstruction and sneezing complaints were frequent in allergic asthmatics and dyspnea was more frequent in non-allergic asthmatics. Most common allergies in allergic asthmatics were house dust mites and pollens. Detection of presence of allergy in asthmatic patients in early period is important in treatment and follows up of patients.
Açıklama
Anahtar Kelimeler
Astım, Allerji, Klinik Özellikler, Solunum Fonksiyon Değerleri, Asthma, Allergy, Clinical Characteristics, Pulmonary Function Parameters
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Düzce Tıp Fakültesi Dergisi
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Scopus Q Değeri
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0
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3
