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Öğe Anterior chamber fixation of a posterior chamber intraocular lens: A novel technique(Medknow Publications & Media Pvt Ltd, 2014) Kükner, Ahmet Şahap; Alagöz, Gürsoy; Erdurmuş, Mesut; Serin, Didem; Doğan, ÜmitWe aimed to evaluate the implantation of a posterior chamber intraocular lens (IOL) in the anterior chamber (AC) with the haptics passing through two iridectomies to the posterior chamber. A total of 33 eyes of 33 patients with inadequate posterior capsular support due to either previous aphakia or posterior capsular rupture during cataract extraction were included in the study. A double iridectomy was performed on all patients using a vitrectomy probe on the midperiphery of the iris. IOLs were implanted in the AC, and the haptics were passed through the iridectomies to the posterior chamber. The mean follow-up time was 25.3 months. AC hemorrhage occurred in five patients during the iridectomy procedure. Corneal edema was detected in eight of 14 patients with primary IOL insertions. Haptic dislocation was detected in only one patient. This technique may be a good alternative to scleral-fixated IOL implantation in eyes with aphakia.Öğe Anterior limbal approach in the treatment of a late and extensive post-traumatic retrobulbar abscess(Slack Incorporated, 2006) Karşıoğlu, Şafak; Serin, Didem; Şimşek, İlke BahçeciThe authors report a case of acute development of an extensive retrobulbar abscess 3 weeks after an orbital floor fracture. Urgent drainage of the abscess was performed by an anterior transconjunctival approach. A dramatic recovery was observed a few days following the operation. The visual acuity increased from hand motions to 0.7 to 0.8 in the early postoperative period and to 1.0 shortly thereafter. The severity of infection, the importance of antibiotic prophylaxis for blowout fractures, and the efficacy of the transconjunctival approach on the final visual and functional outcome are described.Öğe Characteristics of Pellet Injuries to the Orbit(Karger, 2009) Kukner, A. Sahap; Yilmaz, Turgut; Celebi, Serdal; Karslioglu, Safak; Alagoz, Guersoy; Serin, Didem; Acar, M. AkifPurpose: To investigate the features of orbital injuries by pellets fired from the front. Design: Retrospective, 4 cases of pellet injuries. Methods: Five orbits of 4 patients who sustained pellet injuries received from the front were reviewed retrospectively. The course of injury and results were assessed. Radiological examinations were reviewed. The patients were evaluated between December 1996 and June 2004. Results: Five orbits of 4 patients sustained injuries caused by pellets fired from an anterior direction. The globe in the injured orbit was intact in 2 cases. Severe loss of vision was also present in these 2 globes due to optic nerve involvement. Final visual acuity was down to no light perception in 4 eyes and limited to light perception in 1 eye. Conclusions: The prognosis of orbital pellet injuries is, unfortunately, poor. A pellet passing through the floor of the orbit often causes double perforation of the globe and, once in the orbital aperture, it travels towards the apex as a result of the conical shape of the orbit and lodges in the optic canal or its entrance, severely damaging the optic nerve. Surgery or other treatments are usually unsuccessful. Even if the globe is intact, vision is usually severely impaired. Copyright (c) 2009 S. Karger AG, BaselÖğe A comparative study of bimatoprost and travoprost: Effect on intraocular pressure and ocular circulation in newly diagnosed glaucoma patients(Karger, 2008) Alagöz, Gürsoy; Gürel, Kamil; Bayer, Atilla; Serin, Didem; Çelebi, Serdal; Kükner, ŞahapBackground: This study compares intraocular pressure (IOP)-lowering efficacy and retrobulbar hemodynamic effects of bimatoprost and travoprost in patients with newly diagnosed open-angle glaucoma. Methods: Patients were randomly assigned to one of two treatment groups ( bimatoprost group, n = 36; travoprost group, n = 46). IOP levels were measured with Goldmann applanation tonometer. Peak systolic velocity, end-diastolic velocity and resistivity index were obtained for each vessel by color Doppler imaging. Results: Both bimatoprost and travoprost significantly lowered IOP on days 30, 90 and 180 (p < 0.001). There was no significance between the 2 drugs on all follow-up visits. End-diastolic velocity of central retinal artery on day 180 was significantly higher than the value obtained at baseline in both groups. Conclusions: Patients were likely to achieve and maintain low target IOP with both drugs. Both drugs also resulted in improvement in the central retinal artery blood flow. Copyright (c) 2008 S. Karger AG, Basel.Öğe Comparison of ocular surface side effects of topical travoprost and bimatoprost(Karger, 2008) Alagöz, Gürsoy; Bayer, Atilla; Boran, Çetin; Serin, Didem; Kükner, Aysel; Elçioğlu, MustafaPurpose: To compare the subjective symptoms, conjunctival hyperemia, tearing response and conjunctival cytological changes secondary to topical administration of bimatoprost and travoprost for 6 months. Methods: Newly diagnosed primary open-angle glaucoma patients were randomly prescribed bimatoprost (35 cases) or travoprost (42 cases). Two patients in each group were excluded because they did not appear at their appointments regularly. Thus, 33 and 40 patients completed the study in the bimatoprost and travoprost groups, respectively. Redness, itching, foreign-body sensation, pain and discomfort were assessed by a questionnaire, and patients were examined for conjunctival hyperemia. Schirmer's I and break-up time tests were performed, and impression cytology of conjunctiva was evaluated. Results: Subjective symptoms were similar in both groups. The only subjective symptom that changed significantly was redness. The change in conjunctival hyperemia along the study period correlated with the patient-reported redness in both groups, being highest on day 30. Schirmer's test I and break-up time did not change with time and were similar in both groups. The impression cytology grade increased with time in both groups with the only significant difference between groups on day 90 (higher in the bimatoprost group). Conclusion: We observed conjunctival hyperemia as the most common side effect of bimatoprost and travoprost. Tear film functions were not affected by these drugs while cytological alterations were. Copyright (C) 2008 S. Karger AG, Basel.Öğe Effects of intraperitoneal vitamin E, melatonin and aprotinin on leptin expression in the guinea pig eye during experimental uveitis(Wiley, 2006) Kükner, Aysel; Çolakoğlu, Nermin; Serin, Didem; Alagöz, Gürsoy; Çelebi, Serdal; Kükner, A. ŞahapPurpose: To observe ultrastructural changes and leptin expression in the guinea pig eye during experimental uveitis (EU) and the effects of vitamin E, melatonin and aprotinin on leptin expression. Methods: Thirty male guinea pigs were randomly classified into five groups. Group 1 was the control group. Groups 2, 3, 4 and 5 received intravitreal injections of bovine serum albumin (BSA) to induce EU. At the same time on the third day, groups 3 (EU + vitamin E), 4 (EU + melatonin) and 5 (EU + aprotinin) received intraperitoneal vitamin E (150 mg/kg), melatonin (10 mg/kg) and aprotinin (20 000 IU/kg), respectively. On the sixth day, histopathological and clinical scoring of inflammation were performed, and leptin expression was investigated in the retina, choroid, sclera, episclera and cornea, and compared. Result: There was a remarkable increase in leptin expression in the retina, choroid, sclera and episclera in the EU group. Leptin expression in the treatment groups was similar to that in the control group. At light and electron microscopic levels, ganglion cells were oedematous and inner plexiform layer thickness had increased in the EU group retinas. Oedema was decreased in the treatment groups. Comparison of the EU and treatment groups revealed significant differences histopathologically and clinically. Conclusion: Experimental uveitis causes an increase in leptin expression in the retina, choroid, sclera and episclera of guinea pigs. Vitamin E, melatonin and aprotinin inhibit this increase. Leptin seems to be closely related to ocular inflammation.Öğe External dacryocystorhinostomy: Double-flap anastomosis or excision of the posterior flaps?(Lippincott Williams & Wilkins, 2007) Serin, Didem; Alagöz, Gürsoy; Karslıoğlu, Şafak; Çelebi, Serdal; Kükner, ŞahapPurpose: To compare the results of external dacryocystorhinostomy (DCR), using two different patterns of flap anastomosis with creation of both sac and nasal mucosal anterior and posterior flaps: one that includes suturing of both flaps and the other that involves excision of the posterior flaps. Methods. This randomized, clinical trial included 63 consecutive patients undergoing DCR. Patients were alternately assigned to two groups on the basis of the pattern of flap anastomosis. An H-shaped incision was created in the lacrimal sac and the nasal mucosa in all patients. In group A, posterior and anterior flaps were separately approximated; in group B, only the anterior flaps were sutured after resection of both posterior flaps. Postoperative hemorrhage, epiphora, and patency of the tract were assessed on follow-up visits. Final scores and success rates of the two groups were compared by using the Mann-Whitney U and chi(2). Results: The mean length of follow-up was 10.87 +/- 4.75 months for all patients. One patient in group B was lost to follow-up. The difference between the groups in postoperative bleeding, epiphora, and patency scores was found to be statistically insignificant (p = 0.451, p=0.974, p = 0.583, respectively). The final success rates in groups A and B were 93.75% and 96.67%, respectively. There was no statistically significant difference in success rate between the groups (p = 0.593). Conclusions: Our study suggests that DCR with double-flap anastomosis has no advantage over DCR with only anterior flaps. Anastomosis by suturing only anterior flaps and excision of the posterior flaps is easier to perform and does not appear to adversely affect the outcome of DCR surgery.Öğe Eyelid involvement in acanthosis nigricans: the importance of systemic screening(Lippincott Williams & Wilkins, 2005) Serin, Didem; Parlak, Ali Haydar; Alagöz, Gürsoy; Boran, Çetin; Göksügür, NadirA 53-year-old man presented with thickening and hyperpigmentation of the eyelids. After the diagnosis of acanthosis nigricans was made, further investigation of a possible underlying disorder, including biochemical and instrumental examinations, indicated the presence of glucose intolerance, which had been diagnosed 3 years after the clinical appearance of acanthosis nigricans. Eyelid involvement in acanthosis nigricans is rare. Ophthalmologists should be aware of the possibility that acanthosis nigricans can exist in the periocular area and perform a systemic assessment of the patient for the presence of an underlying condition.Öğe Fako-trabekülektomide topikal anestezinin etkinliği ve güvenilirliği(2006) Alagöz, Gürsoy; Serin, Didem; Doğan, Ümit; Yalçın, Ahmet; Kükner, Şahap; Çelebi, SerdarAmaç: Saydam korneal kesili fakoemülsifikasyon cerrahisinde yara yerinden sızıntı nedeniyle tek sütür konulan olgular ile sütürsüz olgular arasındaki cerrahiye bağlı astigmatizmanın (CBA) uzun dönemde karşılaştırılması. Gereç ve Yöntem: Haydarpaşa Numune Eğitim ve Araştırma Hastanesi 2. Göz Kliniğinde Ağustos 2001 ve Temmuz 2003 tarihleri arasında 4 mm saydam kornea kesisi ile fakoemülsifikasyon yapılan ve yara yeri sızıntısı nedeniyle tek 10/0 naylon sütür konulan 15 hastanın 15 gözü (grup 1) ile 4 mm. saydam kornea kesisi yapılmış ve sütür konmamış (grup 2) 18 hastanın 23 gözü çalışmaya dahil edildi. Tüm hastalara katlanabilir göz içi lensi implantasyonu yapıldı. Sütürler 1. ayda alındı. Cerrahi öncesi ve Ocak 2005'de yapılan keratometrik ölçümler arasında grup 1'de ortalama 27.1±5.9 ay, grup 2'de ortalama 25.0 ± 6.3 ay vardı. Ayrıca tüm hastalara pakimetri ve speküler mikroskopi ölçümleri yapıldı. Bulgular: Grup 1'de CBA 1.14±0.53 D iken grup 2'de 0.93±0.53 D'idi. Grup 1'de elde edilen değerler grup 2'den elde edilen değerlerden bir miktar yüksek olsa da iki grup arasında istatistiksel olarak anlamlı bir ilişki mevcut değildi (p=0.226). Grup 1'de merkezi kornea kalınlığı (MKK) 526.1±21.7 mm, merkezi endotel hücre yoğunluğu (MEHY) 1686±313 hücre/mm²; grup 2'de MKK 532.4±30.3 mm, MEHY 1746±381 hücre/mm² olarak saptandı. İstatistiksel olarak anlamlı fark elde edilmedi (sırasıyla p=0.455, p=0.777). Sonuç: Uzun dönemde değerlendirildiğinde tek sütürlü ve sütürsüz saydam kornea kesilerinin yol açtığı astigmatizma arasında önemli bir fark bulunmamaktadır. Bu yüzden ciddi komplikasyonlara yol açabilecek yara yeri sızıntısı varlığında tek sütür koymak cerrahinin güvenliği açısından kazanç sağlayacaktır.Öğe Fakodonezisli katarakt olgusunda iris germe kancaları ile lensin korneaya asılması(2009) Alagöz, Gürsoy; Yalçın, Ahmet; Serin, Didem; Kükner, Ahmet Şahap; Elçioğlu, Mustafa Nuri; Çelebi, SerdalFakodonezisi ve zonüler diyalizi olan hastada lens ön kapsülünün, iris kancaları ile kapsüloreksis kenarlarından korneaya asılmasının fakoemulsifikasyon cerrahisine etkisini bildirmeyi amaçladık. Sol gözde katarakt, fakodonezis ve 180 derece zonül kaybı olan hastaya beş adet iris germe kancası kapsüloreksis sınırından lens ön kapsülüne takıldı. Bu kancalar gerilerek lens korneaya asıldı. Sabit hale gelen lense kapsül germe halkası takılıp fakoemulsifikasyon cerrahisi uygulandı. Cerrahi sonrasında zonül kaybında artış olmadığı tespit edildi Hasta afak bırakıldı. Cerrahiden on beş gün sonra lensin bir bacağı zonül diyalizinin olmadığı sağlam sulkus bölgesine yerleştirilirken diğer bacak ise yeterli kapsül desteğinin olmamasından dolayı irise sütüre edildi. Sonuç olarak, fakodonezisli ve/veya zonül desteği zayıf olan olgularda lensi, iris germe kancaları ile ön kapsülden korneaya sabitlemenin yararlı olduğu kanısındayız.Öğe Flutikazon propiyonat nazal damla tedavisinin göz içi basıncına etkisi(2005) Serin, Didem; Köybaşı, Serap; Alagöz, Gürsoy; Yılmaz, Fahrettin; Kükner, ŞahapAmaç: Flutikazon propiyonat nazal damla tedavisinin göz içi basıncına(GİB) etkisini araştırmayı amaçladık. Yöntem: Nazal polipozis veya allerjik rinit tanısı konularak flutikazon propiyonat nazal damla tedavisi başlanan ve GİB’ nı etkileyebilecek sistemik veya oküler hastalığı bulunmayan 49 erişkin hastanın 98 gözü çalışmaya alındı. Tedaviden önce hastaların GİB’ları ölçüldü. Ortalama 9,53 ± 2,13 haftalık tedavi sonrasında GİB ölçümleri tekrarlanarak tedavi öncesi ve sonrası değerler istatistiksel olarak karşılaştırıldı. Bulgular: Tedavi öncesi ve sonrasında GİB değerlerinde istatistiksel açıdan anlamlı bir fark saptanmadı (sağ ve sol gözler için sırasıyla p=0,516 ve p=0,940). Sonuçlar: Çalışmamız flutikazon propiyonat nazal damlanın glokomla ilgili diğer risk faktörleri olmayan hastalarda GİB’ nda anlamlı bir değişikliğe yol açmadığını göstermiştir. Güvenilirliğin daha iyi değerlendirilebilmesi için daha büyük hasta gruplarına ihtiyaç vardır.Öğe Gözenekli orbital implant takılan hastalarda erken dönemdeki ağrı ve inflamasyonun önlenmesinde vakum tekniğinin etkinliği(2007) Karslıoğlu, Şafak; Serin, Didem; Ziylan, Şule; Yiğit, AygenAmaç: Gözenekli orbital implant (GOİ) takılan hastalarda, eviserasyondan sonra erken dönemde ortaya çıkan şiddetli ağrı ve inflamatuar reaksiyonun önlenmesi için uyguladığımız implantasyon tekniğinin etkinliğini araştırmayı amaçladık. Gereç ve Yöntem: Eviserasyon yapılarak GOİ takılan 40 hasta (çalışma grubu) ve akrilik implant takılan 30 hasta (kontrol grubu) çalışmaya alındı. GOİ takılacak hastalarda implant 50 cc’lik bir enjektöre yerleştirilerek 10 ml bupivakain, 2 ml lidokain, 2 ml gentamisin, ve 2 ml deksametazon çekildi. Enjektörün ucu kapatılıp piston geriye çekilerek negatif basınç oluşturuldu ve gözeneklerin içindeki havanın yerini enjektördeki karışımın alması amaçlandı. Ameliyat sonrası 1., 3. ve 7. günlerde hastalardan hissettikleri ağrıyı 0-10 arasında tanımlamaları istendi. Diğer inflamatuar bulgular (kapaklarda ödem, hiperemi, kemozis) muayene ile 0-3 arası derecelendirildi. Çalışma ve kontrol gruplarında ağrı ve reaksiyon dereceleri Mann-Whitney U testi kullanılarak karşılaştırıldı. Bulgular: GOİ takılan grubun ameliyat sonrası ağrı ve inflamasyon skorları akrilik implant grubuna göre anlamlı derecede düşüktü (p<0.001). GOİ grubunda hiçbir hasta 7. günde ağrı tarif etmeyip, hiçbir hastada kapak ödemi ve kemozise rastlanmadı. Sonuç: Hastalar bu yöntemle ameliyat sonrası erken dönemi rahat geçirmekte, çok daha kısa sürelerde günlük aktivitelerine dönebilmektedir. Hasta konforu, erken rehabilitasyon ve protez kullanmaya erken başlama bakımından, önerdiğimiz tekniğin eviserasyon sonrasında görülen şiddetli ağrı ve inflamasyonun kontrolünde basit ve yararlı bir uygulama olduğu görüşündeyiz.Öğe Implant infection in porous orbital implants(Lippincott Williams & Wilkins, 2006) Karslıoğlu, Şafak; Serin, Didem; Şimşek, İlke; Ziylan, ŞulePurpose. To analyze implant infection in patients with porous orbital implants. Methods: A retrospective analysis of 212 patients with one of five types of porous orbital implants (bone-derived hydroxyapatite [HA], coralline HA, synthetic HA, porous polyethylene, and aluminium oxide) was conducted. Reasons for surgery, type of surgery, type of implant, peg system used, time of pegging, problems before and after pegging, treatment, and follow-up duration were recorded for all patients, along with additional data including time of onset of infection, microorganism cultured, antibiotics used, patient response to antibiotic therapy, additional interventions, and final status for patients with infection. Results: Of the 212 patients with porous orbital implants, 116 (54.72%) were pegged. Implant infection was observed in 11 of 116 patients (9.48%) with pegs, whereas 0% of unpegged implants was infected (p = 0.001). The interval between pegging and the onset of infection was 3 to 83 months (average, 36.27 +/- 29.12 months). Implant exposure was noted in 5 of the 11 patients with infection. Symptoms resolved completely with antibiotic treatment in 7 patients. One patient required implant removal as the result of frequent exacerbations. The remaining 3 patients presented with hemorrhagic, purulent discharge and/or pyogenic granuloma on their last visits after being free of symptoms for 5 to 6 months. Conclusions. Implant infection is a serious problem that requires additional patient visits, intensive antibiotic therapy, surgery, or some combination of these. Existence of a peg system appears to play a role in implant infection. Infection may develop as late as 6 to 7 years after pegging, and the patient should be cautioned about potential late-onset problems. It is possible to control the infection with appropriate antibiotic therapy; removal should be reserved for refractory cases.Öğe Impression cytology of the ocular surface and tear function in patients with periocular vitiligo(Wichtig Editore, 2012) Serin, Didem; Buttanrı, İbrahim Bülent; Parlak, Ali Haydar; Boran, Çetin; Tırak, ErkanPURPOSE. We evaluated the ocular surface and tear function in patients with periocular vitiligo in this prospective, case-control study. METHODS. Sixty eyes of 30 vitiligo patients with periocular involvement and 100 eyes of 50 control subjects were included in the study. Patients and control subjects were compared for Schirmer test and tear film break-up time (BUT) results and impression cytology findings graded according to Nelson's classification. RESULTS. The mean BUT value was 9.5 +/- 4.1 seconds in patients with periocular vitiligo and 13.1 +/- 4.2 seconds in the control group. The difference was statistically significant (p=0.005). Thirty-seven eyes (61.7%) in the vitiligo group and 28 eyes (28.0%) in the control group had BUT values less than 10 seconds (p<0.001). The mean Schirmer test value was 14.6 +/- 4.3 mm in patients with periocular vitiligo and 15.1 +/- 4.4 mm in the control group (p>0.05). Nineteen eyes (31.7%) in patients with periocular vitiligo and 8 eyes (8.0%) in the control group had grade 2-3 changes according to Nelson's classification (p<0.001). Three eyes (5.0%) in the periocular vitiligo group and none of the eyes in the control group had inflammation signs in the impression cytology analysis. CONCLUSIONS. In patients with periocular vitiligo, ocular surface and tear function alterations may occur. Further studies on ocular surface involvement in periocular vitiligo patients may help to increase understanding of the pathophysiology of vitiligo.Öğe Isoametropic amblyopia in highly hyperopic children(Blackwell Publishing, 2007) Ziylan, Şule; Yabaş, Özge; Zorlutuna, Nilüfer; Serin, DidemPurpose: The purpose of this study was to evaluate the visual outcome and associated findings in isoametropic amblyopia due to high hyperopia. Methods: Children with >= 5 D spherical equivalent hyperopia and <= 1.5 D anisometropia and <= 1.5 D cylinder in both eyes were selected. Data were collected on the magnitude of spherical equivalent hyperopia, corrected visual acuity (VA) with the Snellen or Tumbling E charts, age at correction, duration of correction, ocular motility and strabismus. Children who had VA of <= 0.4 in both eyes were defined as having isoametropic amblyopia. Associations between isoametropic amblyopia and factors affecting VA were analysed. Results: A total of 160 children met the criteria. The mean follow-up was 55.8 months. In all, 31 of the children had isoametropic amblyopia. The mean age at presentation was significantly higher (5.5 years versus 4.1 years; p < 0.05) and strabismus was significantly less prevalent (p = 0.001) in the isoametropic amblyopes than in the high hyperopia group as a whole. A total of 83.9% of the isoametropic amblyopes had best corrected VA > 0.5 at the last visit. The duration of optical correction was positively correlated with the last recorded VA measurement. Conclusions: Isoametropic amblyopia is not rare among highly hyperopic children. Visual acuity improves satisfactorily with spectacle correction. The duration of optical correction seems to be an important factor in visual prognosis.Öğe Lipoid proteinozisli dört olguda göz tutulumu(2006) Serin, Didem; Parlak, Ali Haydar; Alagöz, Gürsoy; Boran, Çetin; Kükner, ŞahapCilt ve müköz membranlarda hiyalin benzeri madde birikimi ile karakterize sistemik bir hastalık olan lipoid proteinozisli (LP) dört olgunun göz ve göz dışı bulgularının sunulması amaçlanmıştır. Kapak kenarlarında şişlik, düzensizlik, gözlerde batma, yanma, ve kirpiklerde dökülme gibi şikayetlerle kliniğimize başvuran dört hastanın oftalmolojik muayeneleri yapılarak hastaların göz ve göz dışı bulguları birlikte değerlendirilmiştir. Hastaların göz kapaklarının kenarları LP için tanı koydurucu özellikteki saydam papüllerle kaplıydı. Üç olguda madarozis, iki olguda mevcut kirpiklerde yön değişikliği, iki olguda gözyaşı kırılma zamanında kısalık, ve bir olguda alt punktumlarda stenoz vardı. Tüm olgularda ses kısıklığı, ciltte papüler ve hiperkeratotik lezyonlar, ve ağız mukozasında nodüller izleniyordu. Ayrıca, iki hastada psikiyatrik bozukluk, bir hastada temporal lob kalsifikasyonu mevcuttu. Yanak mukozası ve el derisinden alınan örneklerin histopatolojik incelemesi sonucunda klinik olarak konmuş LP ön tanısı kesinleşti. İki olguda üç aylık asitretin tedavisi sonrasında cilt ve göz kapağı bulgularının gerilediği görüldü. Göz kapaklarında ortaya çıkan tanı koydurucu papüller ve diğer göz bulgularının varlığı nedeniyle LP, göz hekimlerinin akılda tutması gereken sistemik bir hastalıktır. LP tanısı konan hastalarda çok çeşitli göz bulguları olabileceği unutulmamalı, ayrıntılı göz muayenesi mutlaka yapılmalı ve hastaların takibi diğer birimlerle birlikte yürütülmelidir.Öğe Long-term retention of organic foreign body in the anterior chamber : Case report(Ortadogu Ad Pres & Publ Co, 2012) Serin, Didem; Kükner, Şahap; Boran, Çetin; Tırak, ErkanWe aim to present a patient with a well-tolerated piece of organic matter in his anterior chamber following an old, undetected corneal perforation. The patient was a 65-year-old man with a splinter in the anterior chamber noted during examination for a senile cataract. A branch had struck his left eye around the age of 40. There was no inflammation and the foreign body was tolerated for 25 years without any damage to the ocular structures. The foreign body was removed during cataract surgery and examined histopathologically. No complications were observed. The decision to remove a foreign body depends on its potential for subsequent complications. Even though an organic foreign body may remain silent for years in the anterior chamber, its potential for devastating complications should be kept in mind and each patient should be considered on an individual basis.Öğe Non-Kontakt, Goldmann Aplanasyon ve Schiotz Tonometre ölçümlerinin karşılaştırılması(2006) Alagöz, Gürsoy; Serin, Didem; Elçioğlu, Mustafa; Doğan, ÜmitAmaç: Non-kontakt tonometre (NKT), Goldmann aplanasyon tonometresi (GAT) ve Schiotz tonometresi (SCH) ile yapılan göz içi basıncı (GİB) ölçümlerini karşılaştırmak. Gereç ve Yöntem: Polikliniğimize çeşitli şikâyetlerle başvuran 422 hastanın 674 gözü çalışma kapsamına alındı. GİB’ları NKT, GAT ve SCH ile ölçüldü. Sonuçlar istatistiksel olarak karşılaştırıldı. Bulgular: NKT, GAT ve SCH ile ölçülen ortalama GİB değerleri sırasıyla; 18,50 ± 5,49 mmHg, 17,33 ± 5,48 mmHg ve 17,37 ± 5,30 mmHg olarak tespit edildi. NKT ile elde edilen ortalama GİB değerleri GAT ve SCH ölçümlerinden anlamlı derecede yüksek bulundu (p<0.05). GAT ile SCH ölçüm değerleri ise benzer olarak tespit edildi (p>0.05). Sonuç: NKT ile yüksek ölçülen değerlerin diğer yöntemlerle teyit edilmesi gerektiği, düşük değerlerin ise başka bir bulgu söz konusu değilse güvenilir kabul edilebileceği görüşüne varıldı.Öğe Ocular findings in patients with psoriasis(Wiley, 2013) Kılıç, Berna; Doğan, Ümit; Parlak, Ali Haydar; Göksügür, Nadir; Polat, Mualla; Serin, Didem; Özmen, SedatBackground Psoriasis is a chronic inflammatory disease affecting skin, nails, and joints. Although there are not many reports in the literature, ocular findings occur in approximately 10% of patients, in mostly those who have psoriatic arthritis. In this study, we aimed to evaluate eye involvement in psoriasis patients. Methods This study was performed on a total of 100 psoriasis patients and a group of 100 healthy individuals. History was taken from all study and control subjects, and dermatological, systemic, and ophthalmological examinations were performed and Schirmer and BUT values were measured. Constant variables were compared using the t-test, and categorical variables were compared using chi-square test. Relationship between ocular findings and sex, age, duration of psoriasis, PASI score, presence of psoriatic plaques on the eyelid, nail involvement, and psoriatic arthritis was evaluated using logistic regression analysis. Statistical analyses were performed individually for both right and left eyes. Results The number of ocular findings in both eyes in the patient group was found to be statistically higher than that in the control group. Schirmer and BUT values were statistically lower in the patient group than those in the control group. Conclusions Although results of our study support the necessity of routine ophthalmological examination of psoriasis patients for early diagnosis and treatment, we believe that further studies are required on the etiopathogenesis of ocular involvement in psoriasis patients.Öğe Oküloglandüler tularemi tanısı alan iki tularemi olgusu(2010) Bucak, Yasin Yücel; Kükner, Ahmet Şahap; Serin, Didem; Özmen, Sedat; Sırmatel, Fatma; Bal, TayyibeTularemi, Francisella tularensisin neden olduğu zoonotik bir hastalıktır. Bu yazıda kliniğimize preseptal selülit bulguları ile başvuran iki hastayı değerlendirdik. Olgu 1: Otuz iki yaşında bayan hasta bir hafta önce başlayan sağ periorbital şişlik, kızarıklık, preauriküler ve submandibuler bölgelerde şişlik şikayetleri ile başvurdu. Olgu 2; otuzbir yaşında erkek hasta on gün önce başlayan ateş, baş ağrısı, sol periorbital bölgede şişlik, kızarıklık ve preauriküler bölgede şişlik şikayetleri ile başvurdu. Hastalarda klinik ve laboratuvar incelemeleri sonucunda oküloglandüler tularemi tanısı konuldu. Preseptal selülit ve lenfadenopati ile başvuran ateşli hastalarda tularemi ayırıcı tanıda düşünülmeli ve özgül tanı testleri yapılmalıdır.