Yazar "Semerciöz, Atilla" seçeneğine göre listele
Listeleniyor 1 - 16 / 16
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Antimicrobial susceptibility of enterobakteriacea species causing community acquired urinary tract infection: A retrospective study(2007) Ero?lu, Muzaffer; Koço?lu, Esra; Karabay, O?uz; Semerciöz, AtillaIntroduction: The rates of antibiotic resistance in common pathogenic bacteria have been increasing due to high and unnecessary antibiotic use. It can vary according to geographical and regional location. But little is known about the epidemiology of community-acquired antibiotic resistant enterobacteriacea spices in our region. The aim of this study is to assess the antimicrobial susceptibility of enterobacteriacea spices causing community-acquired urinary tract infection in our region. Materials and Methods: Medical records of AIBU microbiology laboratory from August 2004 to August 2006 were retrospectively reviewed to identify all adult patients with community acquired urinary tract infection (UTI). Patients, who had more than three episodes of UTI in the last year, hospitalization in the last month, pregnancy and those with upper UTI were excluded. Susceptibility testing for urinary tract isolates was performed if there were ?100,000 colonies per milliliter. The resistance rates of ampicilline, ciprofloxacine, gentamisin, amikicin, nitrofurantoin and SXT were investigated by Kirby-Bauer disk diffusion technique. Antibacterial susceptibility testing was performed according to the Clinical and Laboratory Standards Institute criteria's (CLSI). Results: During the study period, 3575 urine samples were analyzed and the mean age was 47.2 years (range: 17-74). The overall female to male ratio was 4.8. A total of 305 patients were excluded due to contamination and 697 (21.3%) bacterial isolates were examined in the study. E. coli was the most causative agent (87.1%) and it was followed by Klebsiella pneumonia with a percentage of 9.6%. Highest and lowest antibiotic resistance to Escherichia coli was ampicillin (41%) and nitrofurantoin (0.05%), respectively. Conclusion: Resistance rates of SXT and kinolons are increasing in every day due to high and widespread antibiotic usage. In our region nitrofurantoin and amikacin may be better empiric choices in patients with community-acquired UTI, because their resistance rates are only 0.05% and 3.5%, respectively. Although nitrofurantoin has maintained excellent activity against almost all E. coli strains causing UTI, it is not active against some strains of Enterobacter, Klebsiella and most strains of Proteus species. Urine culture and antimicrobial susceptibility should be essential in the treatment of UTI. Antibiotic resistance rates are changing in every region. Physicians must be educated continuously about the antibiotic resistance and they should know the local antibiotic resistance rates in order to prescribe appropriate antibiotics. Local infection control guidelines must be prepared in every year.Öğe Association of extent and aggressiveness of inflammation with serum PSA levels and PSA density in asymptomatic patients(Elsevier Science Inc, 2007) Kandıralı, Engin; Boran, Çetin; Serin, Erdinç; Semerciöz, Atilla; Metin, AhmetOBJECTIVES The relationship between serum prostate-specific antigen (PSA) levels and histologic prostatic inflammation is controversial. Previous studies were performed using either the intensity or extent of inflammation for grading, with a relatively lower number of specimens. In our study, the inflammation was categorized more profoundly, using both the intensity and the extent of inflammation, to determine the influence of prostatic inflammation on serum PSA levels, percent free PSA (%fPSA), and PSA density (PSAD). METHODS The study included 115 patients who underwent transrectal ultrasound-guided prostate biopsy. To categorize the inflammation, a grading method that included the intensity and extent of inflammation was used. The extent and aggressiveness of inflammation were analyzed. The patients were divided into groups using five grades for the extent and four grades for the aggressiveness of inflammation. The serum PSA Levels, fPSA levels, %fPSA, and PSAD in each group were compared. RESULTS The extent of inflammation grade correlated positively with the serum PSA level (r = 0.423, P <0.001) and PSAD (r = 0.319, P = 0.001). However, a negative correlation was found between the extent of inflammation grade and %fPSA (r = -0.268, P = 0.015). The aggressiveness of inflammation grade correlated positively with the serum PSA level (r = 0.386, P <0.001) and PSAD (r = 0.341, P = 0.001) and negatively with %fPSA (r = -0.289, P = 0.03). CONCLUSIONS If the elevation of serum PSA is thought to be caused by histologic inflammation, it might prevent unnecessary repeated biopsies.Öğe Contractile responses of rabbit bladder neck to adrenaline, acetylcholine and papaverine after doxazosin treatment(Springer, 2007) Eroğlu, Muzaffer; Sezgin, Aysun; Semerciöz, Atilla; Metin, Ahmet; Kandıralı, Engin; Onur, M. AliIt has been demonstrated that long-term administration of doxazosin, an alpha 1 adrenoceptor antagonist, causes an up-regulation in the expression of alpha 1 adrenoceptor subtype mRNAs in the rat genitourinary tract. The aim of this study is to determine whether this up-regulation does have any effect on contractile response of rabbit bladder neck to adrenaline, acethylcholine and papaverin after long-term doxazosin treatment. Fourteen rabbits, treated with doxazosin 3 mg/kg/day p.o for 6 months, and were fed with a diet of standard laboratory rabbit chow (100 g/kg/day). Ten rabbits received the same amount of regular chow but no drug. Contractile responses of rabbit bladder neck to adrenaline acethylcholine and papaverine were measured.Öğe Double intrauterine device: Presented with protruding urethral stone(2008) Kandıralı, Engin; Topçuoğlu, Mehmet Ata; Semerciöz, Atilla; Metin, Ahmetİntrauterin araçlar doğum kontrol yöntemi olarak sık kullanılmaktadır. Uterus perforasyonu ve intrauterin aracın yer değiştirmesi seyrek görülen ciddi bir komplikasyondur. Burada üretra taşı bulgusuyla başvuran hastada saptanan çift intraüterin araç vakası sunulmuştur.Öğe Enterovesical fistula secondary to Crohn's disease mimicking bladder tumor(2006) Kandirali, Engin; Şengül, Neriman; Akkoç, Ali; Türkeli, Vildan; Semerciöz, Atilla; Metin, AhmetIntroduction: Although most fistulas in Crohn's disease are perianal or enterocutaneous, a small portion involves the bladder and urinary system. We describe enterovesical fistulas in a patient with Crohn's disease that presented exclusively as urinary symptoms mimicking bladder tumor. A 55 years-old man presented with lower urinary tract symptoms to our clinic. Ulrasonographic examination showed a normal upper urinary tract and 4 cm papillary bladder tumor. TUR-T was performed and an enterovesical fistula was noticed during operation. Patient underwent abdominal exploration and partial resection of the ileum, ileostomy, and primary bladder repair was performed. Urologic manifestations must be recognized of fistulizing Crohn's disease and urologist should be aware that Crohn's disease may involve the bladder as inflammatory tumor.Öğe Giant condylomata accuminata of scrotum representing as carcinoma (a case report)(Springer, 2006) Metin, Ahmet; Parlak, Ali Haydar; Semerciöz, Atilla; Boran, ÇetinIn this case report a 51-year-old man admitted with a large warty lesion of scrotum representing as carcinoma was presented. A wide surgical resection of the lesion was done with the hystopathologic diagnosis of condyloma accuminata. He was followed for 12 months with satisfactory functional and cosmetic result with no recurrence with the time being.Öğe The inhibitory role of melatonin on isolated guinea-pig urinary bladder: an endogenous hormone effect(Wiley, 2004) Semerciöz, Atilla; Onur, Rahmi; Ayar, Ahmet; Orhan, İrfanOBJECTIVE To investigate the effects of melatonin, an endogenous hormone, on acetylcholine and KCl-induced contractions of isolated guinea-pig detrusor muscle. MATERIALS AND METHODS Detrusor smooth muscle strips isolated from guinea-pig bladders were placed in an organ bath containing physiological saline at 37 degreesC and pH 7.4, constantly bubbled with 95% oxygen and 5% CO2. The effects of cumulatively applied melatonin on the acetylcholine- and KCl-induced contractions of isolated bladder strips were examined using isometric contraction measurements. RESULTS Melatonin (100 and 300 mumol/L) significantly inhibited the peak amplitude of both acetylcholine (10 mumol/L) and KCl (30 mmol/L)-induced contraction of the isolated bladder strips (P < 0.05). Similarly, melatonin caused a significant reduction in the contractile frequency induced by KCl (eight strips) in a concentration-dependent manner, while having no significant effect on the frequency of contractile response to acetylcholine, even at the highest concentration (300 mu mol/L) used (P = 0.58, 14 strips). CONCLUSIONS These results suggest that melatonin inhibits acetylcholine- and KCl-induced contractions in isolated bladder strips from guinea pigs. The endogenous nature of melatonin, with its low side-effect profile, makes it a potentially useful agent to be considered in the medical management of the overactive bladder.Öğe Is only perianal anesthesia with lidocaine-prilocaine cream sufficient to decrease the pain during transrectal ultrasound-guided prostate biopsy? A prospective randomized study(Karger, 2009) Kandıralı, Engin; Ulukaradağ, Emre; Uysal, Bülent; Serin, Erdinç; Semerciöz, Atilla; Metin, AhmetAims: To determine the optimal place to apply the local anesthetic agent and to investigate the efficacy of lidocaine-prilocaine cream on the perianal and intrarectal region during prostate biopsy. Methods: The study included 80 patients. Patients were randomized into four groups: group 1 served as the control group and was administered no anesthesia; group 2 received 5 ml lidocaine-prilocaine cream perianally; group 3 received 5 ml lidocaine-prilocaine cream intrarectally, and group 4 received lidocaine-prilocaine cream perianally and intrarectally. Pain scores during probe insertion, biopsy procedure, and the overall pain score were assessed. Mean pain scores in each group were compared statistically. Results: In group 1, the mean pain score was significantly higher during probe insertion than that during biopsy (p < 0.001). For the mean overall pain scores, there was no significant difference between groups 1 and 3 (p = 0.942), but the results of group 1 were statistically different from groups 2 (p = 0.001) and 4 (p < 0.001). When we compared the biopsy pain scores, there was no significant difference among the groups (p > 0.05). During probe insertion, subjects in groups 2 and 4 reported significantly lower pain scores than the control group (p = 0.002, p = 0.001, respectively). Conclusions: Perianal anesthesia with lidocaine-prilocaine cream may solely be sufficient to decrease the pain during prostate biopsy. Copyright (C) 2009 S. Karger AG, BaselÖğe Isolated renal hydatic cyst; from an unusual course to diagnosis(Springer, 2007) Metin, Ahmet; Kandıralı, Engin; Semerciöz, Atilla; Eroğlu, Muzaffer; Uysal, Bülent; Dadaş, ErdoğanAn isolated renal cyst hydatic in a 65 year old man with unusual symptomatology, course and complications were presented.Öğe Mesane tümörünü taklit eden fistülizan Crohn hastalığı(2006) Kandıralı, Engin; Şengül, Neriman; Akkoç, Ali; Türkeli, Vildan; Semerciöz, Atilla; Metin, AhmetCrohn hastalığında genellikle perianal veya enterokütanöz fistüller gelişmesine rağmen, bazen mesaneye veya diğer üriner sisteme fistüller görülebilir. Burada kliniğimize alt üriner sistem belirtileri ile başvurup mesane tümörü ön tanısı ile ameliyat edilen ve sonucunda mesaneye fistülüze Crohn hastalığı tespit edilen bir olgu sunulmuştur. 55 yaşında erkek hasta kliniğimize alt üriner sistem belirtileri ile başvurdu. Yapılan US’de mesane posteriyöründe 4x4 cm. boyutlarında lümene protrüze papiller oluşum tespit edildi. Hastaya mesane tümörü ön tanısı ile TUR-T operasyonu yapıldı. Rezeksiyon sırasında mesane ile intestinal sistem arasında fistül tespit edildi. Çekilen sistografide kontrast maddenin ileuma geçtiği görüldü. Hastaya daha sonra yapılan batın eksplorasyonunda, mesaneye fistülize terminal ileumu tutan Crohn hastalığı tespit edildi ve ileum rezeksiyonu ve mesane tamiri yapıldı. Crohn hastalarında görülen alt üriner sistem bulgularında, hastalığın mesaneye fistülüze olabileği ve sistoskopi sırasında saptanan fistüllerde de Crohn hastalığı mutlaka akılda tutulmalıdır.Öğe Mesothelial cyst of retroperitoneum(2007) Ero?lu, Muzaffer; Yilmaz, Fahri; Semerciöz, Atilla; Metin, AhmetIntroduction: Right retroperitoneal cyst was diagnosed in a 42 years old woman who had a previous right nephrectomy 28 years ago. The cyst was excised by the same flank incision. Microscopic examination of cyst wall showed that it is lined with a single cuboidal epithelium. The cells were characterized by ample eosinofilik cytoplasm. We didn't find any atypia or mitoses among them. Immunostaining showed that the cyst lining cells were positive for calreitinin and pansitokeratin, PAS+alcian blue also positive in a focal area. These findings suggest that the cyst has a mesothelial origin. In this paper we discuss the retroperitoneal cysts and their treatments.Öğe Milk of calcium cyst mimicking renal calculi: a case report(Springer, 2007) Gürel, Safiye; Metin, Ahmet; Gürel, Kamil; Semerciöz, AtillaA milk of calcium cyst mimicking renal stone in a 51-year-old man was presented to remind the possibility of milk of calcium when a well-defined round density was observed on the renal shadow of the plain abdomen film and the importance of graphics or CT scans taken in different positions to see the changes in the calcium gravidation to prevent unnecessary surgical interventions due to misdiagnosis.Öğe Non-functioning kidney resulted from primary hydatid cyst of the psoas muscle(2006) Kandıralı, Engin; Semerciöz, Atilla; Metin, Ahmet; Eroğlu, Muzaffer; Uysal, BülentPsoas kasında nadiren kist hidatik görülür. Bu vakada primer psoas kası kist hidatiği sonucu oluşmuş nonfonksiyone böbrek vakası bildirilmiştir.Öğe The repair of complex penile defect with composite anterolateral thigh and vascularized fascia lata flap(Turkish Assoc Trauma Emergency Surgery, 2015) Yazar, Şükrü; Eroğlu, Muzaffer; Gökkaya, Ali; Semerciöz, AtillaOne-stage reconstruction of complex penile defects with functional and cosmetic results is a challenging procedure. The selection of proper technique and materials for reconstruction depends on the type of the deficient tissue components, the size of the wound surface, and the donor site. This article presented a case of a partial penile and urethral defect due to an infection in the previous surgical site. The patient was treated with a perforator based pedicled composite anterolateral thigh flap combined with vascularized fascia lata. The urethral defect was reconstructed with the vascularized fascia lata. The remaining part of the flap was used for the resurfacing of the right cavernous body and penile skin defect. There was no fistula and the urinary caliber was accepted as good. The pedicled composite anterolateral thigh flap contains various tissue components suitable for a functional and cosmetic reconstruction of complex penile defects using the one-stage technique.Öğe Retroperitoneal bölgede gelişen mezotelyal kist olgusu(2007) Eroğlu, Muzaffer; Yılmaz, Fahri; Semerciöz, Atilla; Metin, Ahmet28 yıl önce sağ nefrektomi yapılan 42 yaşındaki bayan hastada sağ nefrektomi lojunda tespit edilen kist flank insizyonla girilerek çıkarıldı. Kistin mikroskobik incelemesinde kist duvarının tek sıra küboidal epitelle döşeli olduğu gözlendi. Eozinofilik sitoplazmalı bu hücrelerde mitoz ve atipi yoktu. İmmünohistokimyasal olarak kist epiteli kalretinin ve pansitokeratin pozitifti. Histokimyasal incelemede ise PAS+alcian blue fokal birkaç odakta boyanma gösterdi. Bu bulgular kistin mezotelyal orijinli olduğunu gösteriyordu. Bu yazıda retroperitoneal bölgede görülen kistler ve bunların tedavi yöntemleri tartışıldı.Öğe Toplum kaynaklı erişkin üriner sistem enfeksiyonlarında izole edilen enterobaktericea türlerinin bazı antibiyotiklere duyarlılıkları: Geriye dönük çalışma(2007) Eroğlu, Muzaffer; Koçoğlu, Esra; Karabay, Oğuz; Semerciöz, AtillaYaygın ve düzensiz antibiyotik kullanımına bağlı olarak antibiyotiklere rezistans oranı giderek artmaktadır. Direnç bakımından bölgeler arasında da büyük farklılıklar vardır. Bölgemizdeki direnç oranlarını gösteren bir çalışma yoktur. Bu çalışmanın amacı bölgemizdeki toplum kaynaklı erişkin idrar yolu enfeksiyonlarından izole edilen enterobakteriacea türlerinin bazı antibiyotiklere olan direnç oranlarını araştırmaktır. Bu çalışmada Ağustos 2004-2006 arası dönemde AİBÜ hastanesinde polikliniklerden mikrobiyoloji laboratuvarına gönderilen erişkin hastalara ait idrar kültür örnekleri çalışılmıştır. Kültürlerde 100.000 koloni/ml ve üzerinde üreme gösteren Enterobacteriacea suşlarının antibiyotik duyarlılıkları araştırılmıştır. Ampisilin, siprofloksasin, gentamisin, amikasin, nitrofurantoin ve SXT direnç oranları Kirby-Bauer disk difüzyon yöntemi ile araştırılmıştır. Antibiyotik duyarlılık sonuçlarının değerlendirilmede 2006 yılı Clinical and Laboratory Standards Institute kriterleri esas alınmıştır. Çalışmaya alınan 3575 hastadan kontaminasyonu olan 305 hasta değerlendirme dışı bırakılmıştır. Kalanların 697’sinde (%21,3) üreme olmuştur. Üreme olanların 529’u (%75,9) Enterobacteriacae ailesindendir. En sık izole edilen mikroorganizma Escherichia coli (%87,1) olmuştur. Bunu %9,6 sıklıkla Klebsiella pneumoniae izlemektedir. Bölgemizde E. coli suşlarının en yüksek direnci %41,0 ile ampisilin’e en düşük direnci ise %0,05 nitrofurantoin’e karşı gösterdikleri bulunmuştur. Üriner sistem enfeksiyonlarının tedavisi, kullanılan antibiyotiklere karşı gelişen direnç nedeniyle her geçen gün biraz daha problemli hale gelmektedir. Üropatojenlerin antibiyotiklere direnç oranları ülkeden ülkeye, bölgeden bölgeye değişmektedir. Hekimler bölgesel direnç oranlarını bilmeli ve tedavilerini bu oranlara göre yönlendirmelidirler.
