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Öğe The effect of bilateral sphenopalatine ganglion blockade on postoperative pain, nausea-vomiting, sore throat and larygospasm in fess cases(2008) Karaaslan, Kazim; Yilmaz, Fabrettin; Gülcü, Nebahat; Koço?lu, HasanObjective: We aimed to compare the effects of sphenopalatin ganglion blockade (SPGB) with control group on the early postoperative complications for functional endoscopic sinus surgery (FESS). Method: Sixty patients scheduled for functional endoscopic sinus surgery (FESS) were included in the study. The patients were allocated one of two groups: In Sphenopalatine group (Grup S, n=30), SPGB was applied bilaterally with 2 mL 0.25% bupivacaine 15 min before the end of the surgery. In Control group (Grup K, n=30) 2 mL 0.9 % NaCl solution were injected in both SPG sites. Postoperative pain and analgesic demands were evaluated at 2nd, 6th and 24th hours. The presence of laryngospasm and the frequency of nausea/vomiting in the first 24 hours were also recorded in both groups. Results: Visual analogue scale (VAS) scores were significantly lower in group S at 2nd hour postoperatively. In the first 24 hours, 15 rescue analgesic drugs were needed in 11 cases in group S, but 31 times of 24 cases in group K. In group S the incidence of sore throat in neutral position, sore throat during swallowing and headache was 5, 13 and 15, whereas the incidence were 7, 17 and 22 in group K respectively. Larygospasm was observed in 2 cases of group K, and none in group S. Nausea-vomiting was seen in 6 cases in group S and 10 cases in group K in 24 hours postoperatively but no significant difference in morbidity was detected. Conclusion: Bilateral SPG blockade may provide better analgesia in early postoperative period, when it is compared with control group; but further studies are needed to determine the beneficial effects on larygospasm and nausea-vomiting.Öğe The effect of topical etofenamate with nicotinate on the success of peripheric venous cannulation(2008) Gülcü, Nebahat; Karaaslan, Kazim; Yilmaz, Fahrettin; Koço?lu, HasanObjective: Venipuncture is a commonly performed procedure in hospitalized patients. In this study we aimed to investigate the effects of etofenamate with nicotinate (Thermo-Rheumon® Cream) on the effectiveness on venous cannulation success and procedural pain in pediatric patients. Patients and Methods: Sixty children, aged 7-12 yr, ASA physical status I-II, undergoing elective adenoidectomy and/or tonsillectomy surgery were allocated into two groups. In group etofenamate (n=30), topical agent was applicated on dorsum of the non dominant hand before venipuneture then covered with a transparent dressing for 10 min. In EMLA (cutectic mixture of local anesthetics) group (n=30), cream was applicated 1 hour before the procedure then covered with a transparent dressing. In both groups, venous cannulation was performed with 22 G cannula. Difficulty in cannulation was evaluated by a 4 point scale and procedural pain by facial pain scale (range 0-10) and behavioral response scale (range 0-3) were scored. Results: Significant venipuncture success at the first attempt was observed in group etofenamate compared with EMLA group (p<0.05). The incidences of pruritus, erythema and discomfort were higher in etofenamate group (p<0.05). Both facial and behavioral pain scores were found lower in EMLA group (p<0.05). Conclusion: We concluded that etofenamate with nicotinate may provide significant benefit in augmenting the venipuneture success during intravenous cannula insertion in pediatric population but the effect on procedural pain is limited.Öğe The impact of dexmedetomidine vs midazolam on coagulation factors during nasal surgery(2008) Karaaslan, Kazim; Gülcü, Nebahat; Yilmaz, Fahrettin; Serin, Erdinç; Çolak, Cemil; Koço?lu, HasanObjective: Dexmedetomidine is an ?2 adrenergic receptor agonist and has sedative analgesic properties. We aimed to investigate the effects of dexmedetomidine coagulation system in monitored anesthesia care (MAC) patients, and to compare it with that of midazolam. Material and Methods: Sixty patients undergoing nasal surgery with local anesthesia were recruited. In Group D, dexmedetomidine was infused iv 1 ?g kg-1 over 10 min followed by 0.5 ?g kg-1 h-1. In Group M, midazolam was given iv 40 ?g kg-1 followed by 50 ?g kg-1 h-1. The effects of both drugs on coagulation system were evaluated by means of hemoglobin (Hb), hematocrit (Hte), platelet count, fibrinogen, protrombin time, active partial tromboplastine time (aPTT), INR, protein C, protein S and antitromhin III (ATIII) parameters with preoperatively (t0), early (t1) and 6 hours after postoperatively (t2). Results: Postoperative early (t1) and late (t2) Hb, Hte, aPTT and ATIII were decreased in both groups, and fibrinogen were decreased on these times in group M compared with preoperative values (p<0.05). Fibrinogen values were lower in t1 and t2 measurement in group M compared with group D (p<0.05). Conclusion: We conclude that the uses of dexmedetomidine or midazolam in MAC for nasal surgery do not have any effect on coagulation parameters.