Yazar "Kama, Nuri" seçeneğine göre listele

Listeleniyor 1 - 2 / 2
  • Küçük Resim Yok
    Öğe
    Cholelithiasis and gastrointestinal cancer: Is there a relationship that increases the risk of developing cancer?
    (2020) Özer, Bahri; Çatal, Oğuz; Özer, Songül Peltek; Keyif, Fatih; Şit, Mustafa; Kama, Nuri
    Aim: To investigate the co-existence of cholelithiasis in patients with gastrointestinal (GI) cancer both in preoperative and postoperative periods.Methods: We retrospectively analyzed the data of patients who underwent GI tract cancer surgery in the general surgery clinic of a university hospital between January 2013 and December 2019 for the presence of 'cholelithiasis' in the preoperative and postoperative periods. Age, gender, tumor type and localization and presence of the cholelithiasis in the patients were determined. In addition, the cases were divided into two as upper GI tract and lower GI tract according to tumor location and the relationship with cholelithiasis was evaluated.Results: A total of 680 GI cancer patients were included in the study. Localization of GI cancers were; colon in 211 cases (31%), rectum in 195 cases (28.7%), gastric in 187 cases (27.5%), periampullary region in 55 cases (8.1%), and small intestine in 32 cases (4.7%). In the preoperative period, 69 (10.1%) patients were associated with cholelithiasis. Thirty-one (5.1%) patients had accompanying cholelithiasis in the postoperative period. Coexistence of cholelithiasis according to cancer location was not statistically significant in the preoperative and postoperative periods.Conclusions: Our available data make it difficult to distinguish the roles of cholelithiasis on gastrointestinal cancers, because no statistically causal relationship was found between cholelithiasis and gastrointestinal cancers. However, the role of asymptomatic and symptomatic stones, which may or may not require cholecystectomy, in the development of GI tract cancers should not be ignored.
  • Küçük Resim Yok
    Öğe
    Complete Blood Count parameters could predict malignancy in breast lesions
    (2020) Özer, Bahri; Çatal, Oğuz; Özer, Songül Peltek; Keyif, Fatih; Şit, Mustafa; Kama, Nuri
    Aim: Inflammatory response plays an important role in the development and progression of various cancers, including breast cancer.The aim of present study is determining Complete Blood Count parameters as possible predictors of malignancy in breast lesions.Material and Methods: Patients with BI-RADS-4 breast disease were studied between 2010 and 2017 retrospectively. Patients withlesions detected radiologically were included in the study. According to the histopathological results, the study cohort was dividedinto two groups, either benign or malignant. Final blood counts of the patients before pre-biopsy were evaluated in preoperativeperipheral blood measurements. When blood was taken, care was taken not to have other causes of leukocytosis in the patient.Complete Blood Count parameters were compared in these groups.Results: A total of 331 women with BI-RADS 4 lesions enrolled to the study. Mortality and morbidity were not observed after breastbiopsy in patients. Platelet (p=0.04), platelet to lymphocyte ratio (p=0.006) and red cell distribution width to platelet ratio (p=0.032)values of the patients with BI RADS 4A were found significantly different in the malignant group compared to benign BI RADS 4Agroup. In total BIRADS 4 lesions, the ratio of PLT and RPR was significant in malignant group (p=0.047, p=0.002) in Complete BloodCount parameters compared benign and malignant group.Conclusion: Studies have shown that cancer affects peripheral blood cells positively or negatively. In our study, among peripheralblood cells, platelets were found to be the most affected in cancer patients. The PLT, PLR and RPR values could be valuable inpredicting malignant BIRADS 4 breast lesions.