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    Early neonatal outcomes in patients with late preterm birth
    (2013) Karataş, Ahmet; Albayrak, Mustafa; Keskin, Fatih; Biyik, Ismail; Okur, Mesut; Güneş, Cemalettin; Köse, Seyit Ali
    Objective: Preterm deliveries increased in many countries in recent years. However, despite fetal lung maturity, substantial neonatal morbidity may occur even after 34 weeks of gestation. The aim of this study was to evaluate neonatal morbidity and mortality in women with late preterm births. Design: Retrospective. Setting: Duzce University School of Medicine, Departments of Obstetrics and Gynecology and Pediatrics. Patients: Medical records of 291 pregnant women and newborns born between the 340/7-366/7 weeks of gestation were reviewed. Interventions: The whole population is first divided into two groups as depending on the presence of PPROM or not; and then also divided into-three groups based on the gestational age at delivery as 340/7-346/7 week (Group 1), 350/7-356/7 week (Group 2), and 360/7-366/7 week (Group 3). Main outcome measures: Groups were compared with respect to neonatal complications related to prematurity and early membrane rupture. Results: Of the 291 neonates included in the study, 85 were delivered preterm due to PPROM, 206 were non-PPROM group, and 76 were in group 1, 108 were in group 2, and 107 were in group 3. Sepsis rate was higher in group 1 and 2 compared to group 3 (p=0.016, p=0.029). NICU stay period was longer in group 1 and group 2 than group 3 (p=0.028, p=0.015 respectively). Newborns in group 1 had significantly longer hospital stay than group 3 (p=0.010), and total hospital stay period were significantly higher in newborns with sepsis. Conclusions: The late-preterm infants especially in earlier weeks represent a significantly higher risk category for neonatal complications, and they have a significantly longer NICU and hospital stay period.
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    Trizomi 18 Sendromu: Olgu sunumu
    (2015) Güneş, Cemalettin; Göksügür, Sevil Bilir; Bekdaş, Mervan; Demircioğlu, Fatih
    Trizomi 18 (Edwards sendromu), 18. kromozomun fazlalığı zemininde ortaya çıkan, çoklu konjenital anomalilerle karakterize bir sendromdur. Edwards sendromlu bebeklerde intrauterin gelişme geriliği, mikrognati, mikrosefali, düşük kulaklar, kardiyak anomaliler, üriner sistem anomalileri, gastrointestinal sistem anomalileri ve ekstremite anomalileri gibi bulgular sık görülmektedir. Burada çoklu konjenital anomalisi olan ve Edwards sendromu tanısı konulan 2 aylık bir olguyu sunmayı amaçladık.
  • Küçük Resim
    Öğe
    Vitamin D status in children with attention-deficit-hyperactivity disorder
    (Wiley, 2014) Göksügür, Sevil Bilir; Tufan, Ali Evren; Semiz, Murat; Güneş, Cemalettin; Bekdaş, Mervan; Tosun, Mehmet; Demircioğlu, Fatih
    BackgroundAttention-deficit-hyperactivity disorder (ADHD), one of the most common psychiatric disorders of childhood, has an early onset, affecting 2-18% of children worldwide. The etiopathogenesis of ADHD is obscure. In recent studies, a low level of vitamin D has been found in association with many disorders as well as in neuropsychiatric diseases. The aim of this study was therefore to investigate serum vitamin D level in pediatric ADHD patients. MethodsA total of 60 ADHD patients and 30 healthy controls were included in the study. The age of both groups was in the 7-18-year-old range. Serum 25-OH-vitamin D, calcium, phosphorus and alkaline phosphatase were investigated. ResultsSerum 25-OH-vitamin D was found to be significantly lower in children and adolescents with ADHD compared to healthy controls, and no significant differences were found between the groups in terms of other variables. 25-OH-vitamin D level in the ADHD group and control group was, respectively, 20.9 19.4ng/mL and 34.9 +/- 15.4ng/mL (P = 0.001). ConclusionThere is an association between lower 25-OH-vitamin D concentration and ADHD in childhood and adolescence. To the authors' knowledge this is the first study to investigate the relationship between vitamin D and ADHD in children.