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    A Case with Tracheobronchopathia Osteochondroplastica Presenting Upper Airway Obstruction
    (Duzce Univ, 2009) Akin, Nese; Dumlu, Talha; Balbay, Ege Gulec; Yildirim, Umran; Karatas, Naciye; Kucuk, Ebru; Annakkaya, Ali Nihat
    Tracheobronchopathia Osteochondroplastica (TO) is a rare, slowly progressive benign condition characterized by the presence of bony and cartilaginous nodules in the tracheal and bronchial submucosa. 65 years old man attending to chest disease policlinic with chest pain and upper airway obstruction in his spirometry was diagnosed as TO according to thorax CT and fiberoptic bronchoscopy findings. We have presented herein a rare but benign condition sometimes leading to upper airway obstruction and to emphasize the importance of flowvolume loop in follow up of patient.
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    Correlation between the body fat composition and high sensitive c-reactive protein in Turkish adults
    (2012) Aydın, Mesut; Dumlu, Talha; Alemdar, Recai; Kayapınar, Osman; Celbek, Gökhan; Karabacak, Ahmet; Türker, Yasemin
    objectives. Te adipose tissue is an active immune organ. High sensitive C-reactive protein CRP (hs-CRP) is a strong independent predictor of a possible future myocardial infarction and stroke, and it has also been shown to be related to the sub clinical atherosclerosis. Te aim of this study was to investigate the relation between the body fat composition, metabolic syndrome, and the hs-CRP plasma levels. Methods. Total 246 consecutive Turkish subjects, admitted to the internal medicine clinic with the diagnosis of diabetes mellitus, insulin resistance or metabolic syndrome, were included into the study. Te total body fat composition was measured in every participant with a commercially available bio-impedance meter. Te hs-CRP levels, body composition parameters, and biochemical variables were compared. Results. Te hs-CRP levels increased in parallel with the body weight in Turkish subjects. Tis increase was significant especially in the women. Te waist circumference, body mass index (BMI), and body composition variables (visceral fat level, total body fat, and total body muscle mass) were significant correlates of the hs-CRP. Te waist circumference and BMI were independent predictors of the hs-CRP. Conclusion. Te waist circumference, BMI, and body composition variables (visceral fat level, total body fat and total body muscle mass) were significant correlates of the hs-CRP in Turkish adults. Body weight control may account for an important target especially in patients with the metabolic syndrome.
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    Poor-quality sleep score is an independent predictor of nondipping hypertension
    (Lippincott Williams and Wilkins, 2010) Erden, Ismail; Erden, Emine Cakcak; Özhan, Hakan; Basar, Cengiz; Aydin, Mesut; Dumlu, Talha; Alemdar, Recai
    objective: We aimed to investigate whether there was any association between the nondipping status and sleep quality in relatively young patients with an initial diagnosis of hypertension. METHODS: One hundred and thirty-three consecutive patients, diagnosed to have stage 1 hypertension by their primary physicians, were referred to our study. Patients with a history of use of any antihypertensive medication were excluded. Eligible patients underwent the Pittsburgh Sleep Quality Index (PSQI) survey, which has an established role in evaluating sleep disturbances. All patients underwent ambulatory blood pressure monitoring. RESULTS: There were 71 nondipper patients (mean age 44.3±5.3 years, 33 male/38 female) and 62 dipper hypertensive patients (mean age 43.3±6.3 years, 27 male/35 female). The PSQI scores, globally, were significantly higher in the nondippers compared with the dippers. It was noticed that all the components of the PSQI (sleep quality, sleep latency, sleep duration, sleep efficiency, sleep disturbance, use of sleep medication, and daytime dysfunction) were significantly higher in the nondippers. Correlation analysis showed that systolic blood pressure fall at night was inversely and significantly related with the PSQI (r=-0.46, P<0.001). Logistic regression analysis showed that the PSQI score is an independent determinant for nondipping hypertension (HT) {odds ratio=0.842 [95% confidence interval (CI)=0.748-0.947; P=0.004]}. CONCLUSION: We showed that poor sleep quality was related with a nondipping pattern, and furthermore, it was an independent predictor of nondipping in newly diagnosed stage 1 hypertensive patients. © Lippincott Williams & Wilkins.