Browsing by Author "Yılmaz, İsmail"
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Clinical importance of toxin concentration in Amanita verna mushroom
Yılmaz, İsmail; Kaya, Ertuğrul; Sinirlioğlu, Zeynep Aydın; Bayram, Recep; Sürmen, Mustafa Gani (Pergamon-Elsevier Science Ltd, 2014)Poisoning from Amanita group of mushrooms comprises approximately 3% of all poisonings in our country and their being responsible for nearly the entire fatal mushroom poisonings makes them important. These mushrooms contain ... -
Deadly poisonous turkish mushrooms containing alpha amanitin
Akata, Ilgaz; Kaya, Ertuğrul; Yılmaz, İsmail; Bakırcı, Sinan; Bayram, Recep (Duzce University Medical School, 2015)Mushroom poisoning is still a serious health problem for Turkey. The mushroom species which cause fatal mushroom poisoning have been reported to contain at least 98% alpha-amanitin. The knowledge of the poisonous mushroom ... -
Effects of erdosteine on alpha amanitin-induced hepatotoxicity in mice
Kaya, Ertugrul; Yılmaz, İsmail; Admış, Özlem; Oktay, Murat; Bayram, Recep (Taylor and Francis Ltd, 2016)The aim of this study was to investigate beneficial effects of erdosteine in the alpha amanitine-induced hepatotoxicity in mice. Three hours after giving alpha amanitin (0.5 mg/kg, i.p.) to the mice, they were administered ... -
Evaluation and comparison of alpha- and beta-amanitin toxicity on MCF-7 cell line
Kaya, Ertuğrul; Bayram, Recep; Yaykaşlı, Kürşat Oğuz; Yılmaz, İsmail; Bayram, Sait; Yaykaşlı, Emine; Yavuz, Muhsine Zeynep; Gepdiremen, Ali Akçahan (Tubitak Scientific & Technical Research Council Turkey, 2014)Background/aim: Alpha- and beta-amanitins are the main toxins of the poisonous Amanita phalloides mushroom. Although there are many studies available concerning alpha-amanitin, there are limited data about beta-amanitin ... -
Purification and in vitro toxicity of gamma amanitin
Bakırcı, Sinan; Bayram, Recep; Yılmaz, İsmail; Yaykaşlı, Kürşat Oğuz; Bayram, Sait (Taylor & Francis Ltd, 2015)We aimed to obtain gamma amanitin with high purity through a purification process and compare toxic effects of alpha, beta, and gamma amanitin. Specific concentrations of the toxins (25, 10, 1, and 0.1 mu g/mL) were applied ... -
A retrospective multicenter evaluation of cutaneous melanomas in Turkey
Gamsızkan, Mehmet; Yılmaz, İsmail; Büyükbabani, Nesimi; Demirkesen, Cuyan; Demiriz, Murat; Astarcı, Hesna Müzeyyen (Asian Pacific Organization Cancer Prevention, 2014)Background: We defined melanoma distribution in a large series of Turkish patients and evaluated the prognostic parameters of melanomas. Materials and Methods: A total of 1574 patients' data was retrospectively collected ... -
Toxin content and toxicological significance in different tissues and development stages of Lepiota Brunneoincarnata Mushroom
Yılmaz, İsmail; Bakırcı, Sinan; Akata, Ilgaz; Bayram, Recep; Kaya, Ertuğrul (Taylor & Francis Ltd, 2015)We investigated the quantity and concentration of toxins in different parts and in different growth phases of Lepiota brunneoincarnata mushroom. The amatoxins and phallotoxin levels were measured using the reversed phase ... -
What is the restoring role of chrysin in alpha amanitin toxicity?
Bakırcı, Sinan; Bayram, Recep; Kaya, Ertuğrul; Yaykaşlı, Kürşat Oğuz; Yılmaz, İsmail (Carbone Editore, 2015)Aim: To explore whether chrysin has any protective effect against the deadly effect of alpha amanitin on hepatocytes that is one of the major toxins in the structure of Amanita phalloides, which is considered the most ...