Browsing by Author "Topkara, Kübra Çelik"

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Efficient doxorubicin loading to isolated dexosomes of immature JAWSII cells: Formulated and characterized as the bionanomaterial

Mutlu, Esra Cansever; Kaya, Özge; Wood, Matthew; Mager, Imre; Topkara, Kübra Çelik; Çamsarı, Çağrı; Yıldırım, Arzu Birinci; Çetinkaya, Ayhan (Mdpi, 2020)

Immature dendritic cells (IDc), 'dexosomes', are promising natural nanomaterials for cancer diagnose and therapy. Dexosomes were isolated purely from small-scale-up production by using t25-cell-culture flasks. Total RNA ...
Therapeutic effects of carvacrol on beta-amyloid-induced hippocampal neurotoxicity, oxidative stress, and memory impairment in a rat model of alzheimer's disease

Topkara, Kübra Çelik; Kılınç, Erkan; Çetinkaya, Ayhan; Şaylan, Aslıhan; Demir, Şerif (Wiley, 2022)

Meeting Abstract
Therapeutic effects of carvacrol on beta-amyloid-induced impairments in in vitro and in vivo models of Alzheimer's disease

Topkara, Kübra Çelik; Kılınç, Erkan; Şaylan, Aslıhan; Demir, Şerif; Çetinkaya, Ayhan (WILEY, 2022)

Due to the complex nature of Alzheimer's disease (AD), it is important to investigate agents with multiple effects in the treatment of AD. Carvacrol possesses anti-acetylcholinesterase, anti-oxidant, and neuroprotective ...