Browsing by Author "Kılınç, Erkan"
Now showing items 1-20 of 42
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Capsaicin attenuates excitotoxic-induced neonatal brain injury and brain mast cell-mediated neuroinflammation in newborn rats
Kılınç, Yasemin Baranoğlu; Dilek, Mustafa; Kılınç, Erkan; Torun, İbrahim Ethem; Şaylan, Aslıhan; Düzcü, Selma Erdoğan (Elsevier Ireland Ltd, 2023)Excitotoxicity and neuroinflammation are key contributors to perinatal brain injuries. Capsaicin, an active ingredient of chili peppers, is a potent exogenous agonist for transient receptor potential vanilloid 1 receptors. ... -
Cervical sympathectomy modulates the neurogenic inflammatory neuropeptides following experimental subarachnoid hemorrhage in rats
Dağıstan, Yaşar; Kılınç, Erkan; Balcı, Cemre Nur (Elsevier, 2019)Background: Neuroinflammation is implicated in cerebral vasospasm and brain injuries after subarachnoid hemorrhage (SAH). In addition to classical neuroinflammation with increased inflammatory cytokines, a sterile neurogenic ... -
The Comparison of Effects of Applications of Compound 48/80 and Mast Cell Mediator Suspension on Inflammation in Rats: A Methodological Study for Acute Inflammatory Pain
Objective: Inflammation underlies the pathological basis of most diseases. Substance-P is a key mediator that participates in various inflammatory processes and painful conditions. Mast cells (MCs) have a key role in ... -
The comparison of the effects of application of compound 48/80 and autologous mast cell mediator suspension on plasma substance-P levels and dural mast cells in rats: a methodological study for acute Inflammatory Pain
Kılınç, Erkan; Dağıstan, Yaşar; Çetinkaya, Ayhan; Töre, Fatma (Wiley, 2017)[No Abstract Available] -
The effect of rose oil on penicillin-induced epileptiform activity in rats: An electrophysiological study
Ankaralı, Seyit; Beyazçiçek, Ersin; Kılınç, Erkan; Beyazçiçek, Özge; Özkan, Kayhan; Çetinkaya, Ayhan (2018)Objective: Rose oil (from Rosa damascene) has several effects which are analgesic, antispasmodic, antioxidant and neuroprotective role. Its antiepileptic effect has not been yet studied enough. In the present study, it was ... -
The effect of thymoquinone on the calcitonin gene-related peptide release and dural mast cell degranulation induced by compound-48/80
Kılınç, Erkan; Töre, Fatma (Wiley, 2019)[No Abstract Available] -
Effects and mechanisms of curcumin on the hemodynamic variables of isolated perfused rat hearts
Background/aim: There is no information on the dose–response relationship of curcumin on the hemodynamic variables of the heart at the organ level in isolated perfused rat hearts. We aimed to investigate the effects and ... -
Effects of black cumin seeds and certain species of fungi extracts on the number and degranulation of mast cells in dura mater in rats
Kılınç, Erkan; Dağıstan, Yaşar (Wiley-Blackwell, 2016)[No Abstract Available] -
The effects of certain TRP channels and voltage-gated KCNQ/Kv7 channel opener retigabine on calcitonin gene-related peptide release in the trigeminovascular system
Çıtak, Arzu; Kılınç, Erkan; Torun, İbrahim Ethem; Ankaralı, Seyit; Dağıstan, Yaşar; Yoldaş, Hamit (Sage Publications Ltd, 2022)Background Calcitonin gene-related peptide release in trigeminovascular system is a pivotal component of neurogenic inflammation underlying migraine pathophysiology. Transient receptor potential channels and voltage-gated ... -
Effects of estrogen and progesterone on the neurogenic inflammatory neuropeptides: Implications for gender differences in migraine
Çetinkaya, Ayhan; Kılınç, Erkan; Çamsarı, Çağrı; Ögün, Muhammed Nur (Springer, 2020)Neurogenic inflammation including calcitonin gene-related peptide (CGRP) and substance-P (SP) release plays a pivotal role in migraine pathogenesis. Prevalence of migraine is similar to 3 folds higher in women than in men, ... -
Effects of Nigella sativa seeds and certain species of fungi extracts on number and activation of dural mast cells in rats
Kılınç, Erkan; Dağıstan, Yaşar; Kotan, Batuhan; Çetinkaya, Ayhan (Akademiai Kiado Rt, 2017)In this study, we aimed to investigate the effects of Nigella sativa seeds and certain species of fungi extracts on the number and degranulation states of dural mast cells in rats. Rats were fed ad libitum with normal tap ... -
The effects of reactive oxygen species and TRPA1 receptors on nociceptive firing and calcitonin gene-related peptide release in rat meninges
Kılınç, Erkan; Töre, Fatma; Giniatullin, Rashid (Wiley-Blackwell, 2016)[No Abstract Available] -
Effects of stellate ganglion block on healing of fractures induced in rats
Kızılay, Hasan; Çakıcı, Hüsamettin; Kılınç, Erkan; Fırat, Tülin; Kuru, Tolgahan; Şahin, A. Alper (Hindawi Ltd, 2020)Objective. Sympathetic blocks are used as an adjunct for pain management in the treatment of orthopedic and traumatic conditions. Stellate ganglion (ganglion stellatum) provides sympathetic innervation of the head, neck ... -
Esculetin alleviates pentylenetetrazole-induced seizures, cognitive impairment and pro-inflammatory cytokines and suppresses penicillin-induced epileptiform activity in rats
Danış, Ayşegül; Kılınç, Yasemin Baranoğlu; Torun, İbrahim Ethem; Hancı, Fatma; Kılınç, Erkan; Ankaralı, Handan (Pergamon-Elsevier Science Ltd, 2023)Aims: To investigate the effects of different doses of esculetin on epileptiform activity, behavioral seizures, memory impairment, and cortical and hippocampal NF-Kappa B, as a mediator of pro-inflammatory gene induction, ... -
Global evaluation of coronavirus disease 2019 cases and clustering of similar countries
Ankaralı, Handan; Ankaralı, Seyit (KARE PUBL, 2021)OBJECTIVE: It was aimed to be obtained descriptive values with respect to the outbreak time course, demographic structure, and symptom distribution by the help of case-based data, and to be compared countries by being ... -
Hunting for origins of migraine pain: cluster analysis of spontaneous and capsaicin-induced firing in meningeal trigeminal nerve fibers
Zakharov, Andrey; Vitale, Carmela; Kılınç, Erkan; Koroleva, Kseniia; Fayuk, Dmitry (Frontiers Media Sa, 2015)Trigeminal nerves in meninges are implicated in generation of nociceptive firing underlying migraine pain. However, the neurochemical mechanisms of nociceptive firing in meningeal trigeminal nerves are little understood. ... -
In vitro effects of direct and alternate electric fields on saos-2 cell line
Fidan, Murat; Çamsarı, Çağrı; Çoban, Melih; Çetinkaya, Ayhan; Kılınç, Erkan (Verduci Publisher, 2019)Objective: The exposure of electric fields in daily life is greatly increased through the use of electronic devices, new transportation technologies and various other devices. Alternate current (AC) and direct current (DC) ... -
An Investigation of Lung Mast Cell Behavior in a Rat Model of Migraine: Implications for Migraine Headache
Kılınç, Erkan; Balcı, Cemre Nur (2018)Aim: In this study, we aimed to investigate the potential role of lung mast cells in migraine by using a nitroglycerin-induced migraine model in rats. Materials and Methods: Thirty-five adult male Wistar rats were divided ... -
Lomber Disk Hernisi ve Hemogram Parametreleri Arasında Bir Bağlantı Var mı?
Amaç: Enflamatuvar mekanizmalar disk hernisi ile ilişkili bel ağrısının patogenezinde önemli bir rol oynamaktadır. Rutin hemogram testlerindeki yeni ve umut vadeden enflamatuvar belirteçler ortalama trombosit hacmi (mean ...
