Şahin, ŞafakSarıkaya, SavaşAlçelik, AytekinErdem, AlimTaşlıyurt, TürkerAkyol, LütfiAltunkaş, FatihAktaş, Gülali2021-06-232021-06-2320130393-63842283-9720https://www.actamedicamediterranea.com/archive/2013/medica-4/neutrophil-to-lymphocyte-ratio-is-a-useful-predictor-of-atrial-fibrillation-in-patients-with-diabetes-mellitus/documenthttps://hdl.handle.net/20.500.12491/7672Background & aims: Diabetes mellitus is an important risk factor for the development and progression of atrial fibrillation. There are several possible pathways to the mechanisms of atrial fibrillation associated with diabetes mellitus. Long-term inflammation is one of the mechanisms. To our knowledge, there is not a study that consistent evidence about the link between atrial fibrillation and neutrophil to lymphocyte ratio in diabetes mellitus. In the study, we aimed to investigate the possible association of chronic atrial fibrillation with neutrophil to lymphocyte ratio in patients who have type 2 diabetes mellitus. Methods: A total of 812 diabetes mellitus patients were retrospectively screened between March 2012 and March 2013. Patients with diabetes mellitus and a history of electrocardiographically documented persistent atrial fibrillation were assigned to the atrial fibrillation group (Group I) (n=72) and, if no history of atrial fibrillation was evident, patients were placed in the normal sinus rhythm group (Group 2) (n=72). Results: Neutrophil to lymphocyte ratio was different among patients with atrial fibrillation and without atrial fibrillation (2.87+/-1.3 vs. 2.2+/-1.56 p=0.019). Cut-off point of Neutrophil to lymphocyte ratio was at 2.38, and sensitivity, specificity was 75.7% and 67% respectively Conclusions: In conclusion, we suggest that neutrophil/lymphocyte ratio increase in diabetic patients with atrial fibrillation when compared to diabetic patients without atrial fibrillation. We think that neutrophil to lymphocyte ratio can be used as a marker of development of atrial fibrillation in diabetic patients.eninfo:eu-repo/semantics/closedAccessDiabetes MellitusAtrial FibrillationNeutrophil to Lymphocyte RatioInflammationArticle2948478512-s2.0-84896702164N/AWOS:000330151200041Q4