Şenel, Ferda MahmutAkman, Ramazan YavuzArıkan, A. YüselGürdal, MesutCan, Cevat2021-06-232021-06-2319990301-1623https://doi.org/10.1023/A:1007117917974https://hdl.handle.net/20.500.12491/4623The safety and histopathologic effects of polytetrafluoroethylene (Gore- Tex) grafts in reconstruction of the urinary bladder were examined. Following partial excision of the bladder Gore-Tex was placed, and the rats were sacrificed at days 7, 14 and 30. Gore-Tex did not cause urine infection, and there was no peritonitis or sepsis in any of the rats. Inflammation around the Gore-Tex diminished after four weeks. Some mononuclear cells and exudate were observed on the inner surface of the Gore-Tex. There was no inflammation or fibrosis in the mucosa and muscular layers of the remaining bladder. In this study the Gore-Tex graft was found to be an infection resistant, urine impermeable material, with no adverse effects on the urinary bladder. Gore- Tex is suggested as a safe material for the reconstruction of the urinary bladder.eninfo:eu-repo/semantics/closedAccessPolytetrafluoroethyleneUrinary BladderArticle10.1023/A:1007117917974313313319106729502-s2.0-0033451770Q2