Duman, Tuba TaslamacıoğluAktaş, GülaliAtak, Burçin MeryemKoçak, Mehmet ZahidErkuş, EdipŞavlı, Haluk2021-06-232021-06-2320191680-69051729-0503https://doi.org/10.4314/ahs.v19i1.35https://hdl.handle.net/20.500.12491/10096Background: Type 2 diabetes mellitus is associated with chronic low grade inflammation. One of the novel inflammatory markers is hemogram derived neutrophil to lymphocyte ratio (NLR). Objective: We aimed to compare NLR levels of diabetic subjects and healthy controls and to observe possible correlation between NLR and HbA1c. Methods: Medical data of type 2 diabetic subjects admitted to out-patient clinics of our institution between April to July in 2017 were obtained from database and retrospectively analyzed. Control group was chosen from healthy subjects who visited our institution for a routine check-up. Anthropometric measures, laboratory data, including, HbA1c, NLR were recorded. Results: Median NLR of the type 2 DM group 2.44 (1.9) was significantly elevated when compared to healthy controls (1.5 (0.9), (p<0.001). In addition, a Pearson's correlation test revealed that NLR was strongly correlated with age (r=0.26, p=0.008), fasting plasma glucose (r=0.38, p<0.001), and HbA1c (r=0.49, p<0.001). Conclusion: Elevated NLR in otherwise healthy subjects may be indicative of underlying impaired glucose metabolism and moreover, NLR should be used as a marker of diabetic control level in addition to HbA1c in type 2 diabetic subjects.eninfo:eu-repo/semantics/openAccessType 2 Diabetes MellitusHbA1cNeutrophil to Lymphocyte RatioInflammationArticle10.4314/ahs.v19i1.3519116021606311489892-s2.0-85065538268Q3WOS:000465469000035Q4