Yetkin, ErtanHeper, GülümserŞenen, Kubilay2021-06-232021-06-2320100021-9150https://doi.org/10.1016/j.atherosclerosis.2009.09.024https://hdl.handle.net/20.500.12491/6725Dear Editor, We have read the article published by De Luca et al. [1] with great interest. In their report, they have investigated the possible association of mean platelet volume (MPV) with coronary artery disease (CAD) in a very large consecutive cohort of patients undergoing coronary angiography. Briefly, they have used the number of diseased vessels as a measure of extent of CAD and carotid intima-media thickness to assess the relation between atherosclerosis and MPV. It has been concluded out that MPV is not related to the extent of CAD, carotid intima-media thickness and cannot be considered as a risk factor for CAD. Additionally no relationship has been observed between MPV and platelet aggregation in a subgroup of patients.eninfo:eu-repo/semantics/closedAccessMean Platelet Volume (MPV)Coronary Artery DiseaseAcute Coronary SyndromePlatelet ActivationLetter10.1016/j.atherosclerosis.2009.09.0242092336336198194542-s2.0-77950021160Q1WOS:000276158000004Q1