Dönmez, İbrahimMemioğlu, TolgaAcar, EmrahErdem, Fatma2023-11-102023-11-102022Donmez, I., Memioglu, T., Acar, E., Erdem, F. (2022). Evaluation of the effects of 3D mapping ablation on atrial conduction times in patients with paroxysmal atrial fibrillation. Annals of Clinical and Analytical Medicine, 13, 1373-1377.2667-663Xhttp://dx.doi.org/10.4328/ACAM.21367https://hdl.handle.net/20.500.12491/11823Aim: Atrial fibrillation (AF) causes structural, electrical, and cellular remodeling in the atrium. Evaluation of intra-and interatrial conduction time, indicates structural and electrical remodeling in the atrium. This study aimed to evaluate the effect of pulmonary vein isolation applied with radiofrequency ablation (RF) therapy on intra-and interatrial conduction time and to investigate the structural and electrically remodeling after treatment.Material and Methods: Fifty-two patients with symptomatic PAF despite at least one antiarrhythmic drug and without structural heart disease were included in the study. Two patients were excluded because of complications developed during and after the operation. Fifty patients (28 female; mean age: 51.68 +/- 11.731; mean left atrial diameter: 36.79 +/- 4.318) who underwent CARTO (R) 3D pulmonary vein isolation applied with the RF ablation system were followed-up. Intra-and inter-atrial electromechanical delay was measured in all patients using tissue doppler echocardiography before and three months after RF ablation.Results: All intra-and interatrial conduction times were significantly decreased 3 months after RF ablation procedure (PA lateral p = 0.022; PA septum p = 0.002; PA tricuspid p = 0.019, interatrial conduction delay p= 0,012, intra-atrial conduction delay p = 0.029).Discussion: The results of our study suggest that providing stable sinus rhythm with RF ablation may slow down, stop or even improve structural remodeling at substrate level secondary to AF even in patients with paroxysmal AF who did not yet develop atrial fibrosis and permanent structural changes.eninfo:eu-repo/semantics/openAccessPulmonary Vein IsolationRadiofrequency AblationAtrial Conduction TimeTissue Doppler EchocardiographyRythm ControlArticle10.4328/ACAM.21367131213731377N/AWOS:000895809100017N/A