Yıldız, Serpil KuyucuKöybaşı, SerapTürkoğlu, Şule AydınYıldız, NebilKorkmaz, BektaşAkyürek, Fatma2021-06-232021-06-2320071388-2457https://doi.org/10.1016/j.clinph.2007.05.069https://hdl.handle.net/20.500.12491/6024Objective: To investigate the sympathetic nervous system activity in Meniere's disease (MD) by recording sympathetic skin responses (SSRs) from the postauricular region (PA). Methods: Twenty-one patients with definite unilateral MD diagnosis and 12 healthy volunteers were studied by evoking right and left PA-SSRs with electrical stimulation of the left median nerve at the wrist in attack and interval periods of MD. Mean latencies and maximum amplitudes were used in statistical analyses. Results: In unilateral definite MD patients, the mean latencies were longer and the maximum amplitudes were smaller on the involved ear side than those on the normal ear side (p < 0.01 for both amplitude and latency) and than those from the controls (p < 0.01 and p < 0.05). In three patients, there was no detectable PA-SSR on the involved ear side while there were SSRs on the healthy side. In four patients, the responses were absent bilaterally during the attack period. Conclusions: There is a marked asymmetric sympathetic hypofunction in the area of the PA region of the involved ear in MD patients. Significance: The PA region is a new site for recording sympathetic skin responses. PA-SSR is a useful tool to investigate sympathetic nervous system function in MD patients. (C) 2007 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.eninfo:eu-repo/semantics/closedAccessSympathetic Skin ResponsePostauricular SSRElectrical StimulationMeniere's DiseaseAutonomic DysfunctionArticle10.1016/j.clinph.2007.05.069118919911998176046922-s2.0-34547523661Q1WOS:000249364200013Q2