Yasar, Aysenur BuzYuzok, Ruveyde BegumDagistan, Emine2024-09-252024-09-2520241305-3612https://doi.org/10.4274/dir.2024.232586https://hdl.handle.net/20.500.12491/14005PURPOSE In this case-control study, we aimed to evaluate how muscle volume affects pelvic floor function by analyzing the levator ani muscle (LAM) using volumetric segmentation in addition to standard magnetic resonance (MR) defecography assessments. METHODS We enrolled 85 patients with varying degrees of pelvic floor dysfunction (PFD) and 85 age- and gender-matched controls in this retrospective study. All patients had MR defecography images, while all controls had pelvic MR images obtained for other reasons. Group comparisons were performed using independent samples t-tests and Mann-Whitney U tests. The receiver operating curve (ROC) was constructed to establish a cut-off value for a normal LAM volume. Interrater reliability was assessed by calculating the intraclass correlation coefficient. A P value of less than 0.05 was considered statistically significant. RESULTS Volumetric measurements revealed that the control group had higher LAM volumes, and the ROC curve analysis indicated a cut-off value of 38934.3 mm 3 with a sensitivity of 0.812 and specificity of 0.8 for PFD assessment using LAM volumetric measurement. Gender did not significantly affect LAM volume in the control group. CONCLUSION Alongside the useful structural and functional information acquired from MR defecography images, volumetric analysis, and three-dimensional reconstructions of LAM may help to improve the accuracy of the diagnosis.eninfo:eu-repo/semantics/openAccessSegmentation levator ani musclepelvic floor dysfunctionmagnetic resonance defecographyvol-umetric measurementArticle10.4274/dir.2024.232586304220227383757672-s2.0-85192787085Q2WOS:001274047800002N/A