Uysal, ÖzgeUstaoğlu, GülbaharBehçet, MustafaAlbayrak, ÖnderTunalı, Mustafa2024-02-062024-02-062022Uysal, Ö., Ustaoğlu, G., Behçet, M., Albayrak, Ö., & Tunalı, M. (2022). Applying nano-HA in addition to scaling and root planing increases clinical attachment gain. Journal of Periodontal & Implant Science, 52(2), 116.2093-22782093-2286http://dx.doi.org/10.5051/jpis.2102080104https://hdl.handle.net/20.500.12491/11981This study was supported by Bolu Abant Izzet Baysal University Scientific Research Center (Project No. 2020.06.05.1443).Purpose: This study evaluated the efficacy of treating periodontitis using subgingival nano-hydroxyapatite powder with an air abrasion device (NHAPA) combined with scaling and root planing (SRP). Methods: A total of 28 patients with stage III periodontitis (grade B) were included in this study, although 1 was lost during follow-up and 3 used antibiotics. The patients were divided into a test group and a control group. All patients first received whole-mouth SRP using hand instruments, and a split-mouth approach was used for the second treatment. In the test group, the teeth were treated with NHAPA for 15 seconds at 70% power per pocket. Subgingival plaque samples were obtained from the 2 deepest pockets at the test and control sites before treatment (baseline) and 3 months after treatment. The full-mouth plaque index (PI), gingival index (GI), papillary bleeding index (PRI), bleeding on probing (BOP), probing depth (PD) and clinical attachment level (CAL) were recorded at baseline and at 1- and 3-month post-treatment. Real-time polymerase chain reaction was used to determine the colonisation of Treponema denticola (Td), Porphyromonas,gingivalis(Pg), and Aggrega Odder actinomycelemcomitans in the subgingival plaque. Results: From baseline to the first month, the test group showed significantly larger changes in BOP and CAL (43.705%+/- 27.495% and 1.160 +/- 0.747 mm, respectively) than the control group (36.311%+/- 27.599% and 0.947 +/- 0.635 mm, respectively). Periodontal parameters had improved in both groups at 3 months. The reductions of PI, GI, BOP, PD, and CAL in the test group at 3 months were greater and statistically significant. The total bacterial count and Td and Pg species had decreased significantly by the third month in both groups (P<0.05). Conclusions: Applying NHAPA in addition to SRP improves clinical periodontal parameters more than SRP alone. Subgingival NHAPA may encourage clot adhesion to tooth surfaces by increasing surface wettability.eninfo:eu-repo/semantics/openAccessAnaerobic BacteriaHydroxyapatitesPeriodontal DebridementSubgingival Plaque RemovalChronic PeriodontitisNonsurgical TreatmentArticle10.5051/jpis.2102080104522116126355055732-s2.0-85132666308Q3WOS:000797190000003Q4