An efficient one-pot synthesis of 5-(substituted amino)-1,2,4-thia- and -oxa-diazoles

Dürüst, YaşarYıldırım, MuhammetAycan, Aslı2021-06-232021-06-2320081747-5198https://journals.sagepub.com/doi/pdf/10.3184/030823408784549933https://hdl.handle.net/20.500.12491/6304A general protocol for the synthesis of 5-(substituted amino)-1,2,4-thiadiazoles by the cyclocondensation reaction of amidoximes with N-substituted thioureas in the presence of KF/Al2O3, and of 5-(cyclohexylamino)-1,2,4-oxadiazoles with DCC in the presence of KF/Al2O3 and thiourea, is described. The structures of the new compounds were elucidated by spectroscopic and physical data, and the crystal structure determination by X-ray diffraction of three examples.eninfo:eu-repo/semantics/closedAccessAmidoximes1,2,4-thiadiazole1,2,4-oxadiazolesThioureasKF/Al2O3 CatalysisAn efficient one-pot synthesis of 5-(substituted amino)-1,2,4-thia- and -oxa-diazolesArticle10.3184/030823408X31727242352392-s2.0-66149148631Q3WOS:000260048800019N/A