Olutaş, Elif BernaKartal, Necla BüşraYıldırım, Arzu Birinci2023-11-162023-11-162022Olutas, E. B., Kartal, N. B., & Yildirim, A. B. (2022). Self-assembly, surface, antibacterial, and solubilization properties of phenylglycine type amino acid-based cationic surfactants. Journal of Molecular Liquids, 367, 120528.1873-31660167-7322http://dx.doi.org/10.1016/j.molliq.2022.120528https://hdl.handle.net/20.500.12491/11842The authors are thankful to the Research and Development Foundation of Bolu Abant Izzet Baysal University (Grant No. 2020.03.03.1482) for the financial support of this work.Here, synthesis and characterization of amino acid-based chiral cationic surfactants containing phenyl-glycine moiety, L-phenylglycine hydrochloride octyl ester (L-PgC8E), and L-phenylglycine hydrochloride decyl ester (L-PgC10E), and their physicochemical properties such as the micellization, surface, and volu-metric parameters have been reported. In addition, the structural analyses of the aggregates of these esters were also performed by dynamic light scattering (DLS) and transmission electron microscopy (TEM) techniques. It was found that the presence of a phenyl ring in the head group promoted the micelle formation leading to a smaller critical micelle concentration (CMC) value and enhancing the adsorption efficiency with an increased hydrocarbon chain. Besides, the antibacterial activities of the synthesized surfactants have been explored against three Gram-positive (G+) and seven Gram-negative (G-) bacteria below and above their CMC values by measuring the zone of inhibition diameter. The results showed that L-PgC8E was more active than L-PgC10E against all bacteria; this was explained by the formation of smal-ler and less stable aggregates that could interact efficiently with the bacterial membrane. Furthermore, the solubilization power (SP) of both surfactants for Methyl Red (MR) was determined, and it was found that L-PgC10E with a longer hydrocarbon chain and forming a large hydrophobic area by its large aggre-gates showed a more efficient solubilizing power.(c) 2022 Elsevier B.V. All rights reserved.eninfo:eu-repo/semantics/closedAccessAmino Acid-Based SurfactantMicellizationSurface TensionCritical Micelle ConcentrationSodium Dodecyl-Sulfate2 Organic-DyesArticle10.1016/j.molliq.2022.1205283671142-s2.0-85139594857Q1WOS:000869467100004Q1