Erdurmuş, MesutSimavlı, HüseyinAydın, Bahri2021-06-232021-06-232014978-0-12-404606-1; 978-0-12-401717-7https://doi.org/10.1016/B978-0-12-401717-7.00003-4https://hdl.handle.net/20.500.12491/8104The human lens grows continuously throughout life, due to the addition of new subcortical lens fibers. A cataract, which is any opacity within a lens, is the most prevalent cause of visual impairment in elderly people, and it remains the most common cause of blindness in the developing world. Morphologic types of age-related cataracts are nuclear, cortical, subcapsular, and mixed lenticular opacities. Numerous potential risk factors have been linked to cataract development, including smoking, corticosteroid use, diabetes, family history, myopia, obesity, ultraviolet light exposure, environmental factors, and genetics. Pathogenic mechanisms that lead to cataracts may involve oxidative stress, advanced glycation end products, aggregation of lens proteins, Na+/K+ ATPase underaction, polyol pathways, and genetic abnormalities. Management of a visually significant cataract is primarily surgical. Cataract surgery and intraocular lens implantation is the most frequently performed operation in older individuals. The preferred technique for removing an opacified lens is extracapsular cataract extraction, most commonly by phacoemulsification.eninfo:eu-repo/semantics/closedAccessAge-related CataractCataractCataract SurgeryEpidemiology of CataractPathogenesis and Risk FactorsPhacoemulsificationBook Chapter10.1016/B978-0-12-401717-7.00003-421282-s2.0-84943279233N/AWOS:000337276300004N/A