Kaya, GulKoc, Eda OndulOzdemir, SadinYalcin, M. SerkanOcakoglu, KasimDizge, Nadir2024-09-252024-09-2520240273-22891559-0291https://doi.org/10.1007/s12010-024-04910-whttps://hdl.handle.net/20.500.12491/13471Chromium aluminum carbide (Cr2AlC) MAX phase and Cr2CTx (MXene-Cr) were synthesized by the pressureless sintering method and hydrothermal method, respectively. In addition to this, the free radical scavenging activities (FRSA) of MAX-Cr phase and MXene-Cr compounds were tested and compared with ascorbic acid and trolox as standard compounds. The obtained FRSA results of MAX-Cr phase and MXene-Cr were 42.82 and 59.64%, respectively, at 100 mg/L concentration. MXene-Cr showed a 66.90% inhibitory effect on alpha-amylase at 200 mg/L. The DNA nuclease activity of compounds was determined to be extremely satisfactory at 50, 100, and 200 mg/L concentrations. Moreover, the prepared MAX-Cr phase and MXene-Cr were investigated for antimicrobial activity against six bacterial and two fungal strains by the broth microdilution method. Compounds provided more significant inhibition against Gram-positive bacteria than Gram-negative bacteria and fungi. MAX-Cr phase and MXene-Cr almost completely inhibited microbial cell viability at a 25 mg/L concentration. Additionally, MXene-Cr showed 89.86% and 87.01% antibiofilm activity against S. aureus and P. aeruginosa, respectively, while the antibiofilm activity of the MAX-Cr phase was over 90%.eninfo:eu-repo/semantics/closedAccessCr2AlC MAX phase (MAX-Cr)Cr2CTx (MXene-Cr)AntioxidantAntimicrobialDNA cleavageBiofilm inhibitionArticle10.1007/s12010-024-04910-w385388712-s2.0-85188820827Q2WOS:001194763400002N/A