Deniz, Ömür GülsümKaplan, Süleyman2023-06-092023-06-092022Deniz, Ö. G., & Kaplan, S. (2022). The effects of different herbals on the rat hippocampus exposed to electromagnetic field for one hour during the prenatal period. Journal of Chemical Neuroanatomy, 119, 102043.0891-06181873-6300http://dx.doi.org/10.1016/j.jchemneu.2021.102043https://hdl.handle.net/20.500.12491/11095The present research was supported by the Ondokuz Mays Univer-sity Project Management Office (PYO.TIP.1901.14.015) .The purpose of this study was to highlight the possible effects on the hippocampus of the electromagnetic field (EMF) emitted by mobile phones, and to investigate whether these potential effects can be reduced using various antioxidant substances. Twenty-seven female Wistar albino rats were divided into nine equal groups, each containing three pregnant rats aged 8-10 weeks and weighing 200-250 gr. The EMF groups were exposed to 900 Megahertz (MHz) EMF for 1 h (hr) a day for 21 days. No EMF exposure was applied to the Cont and also the groups given only Garcinia kola (GK), Momordica charantia (MC), and thymoquinone (TQ). The Sham group was kept in the polycarbonate EMF exposure system, but was not exposed to EMF. Four weeks after birth, rat pups were subjected to behavioural tests. Brain tissue samples were evaluated using histological, stereological, functional, and immunohistochemical methods. The numbers of pyramidal neurons in the rat cornu ammonis (CA) were determined using the optical fractionator method. Superoxide dismutase (SOD) and catalase (CAT) enzyme activities in the blood samples were also evaluated. The analysis data indicated that total pyramidal neuron numbers were decreased significantly in the CA of the EMF (1 hr) group (p < 0.01). Our results also showed that the protective effect of MC was more potent than that of the other antioxidant substances (p < 0.01). A 900 MHz EMF can cause deleterious changes in the brain. It can also be suggested that GK, MC and TQ are capable of reducing these adverse effects.eninfo:eu-repo/semantics/closedAccessElectromagnetic FieldHippocampusGarcinia KolaMomordica CharantiaThymoquinoneStereologyArticle10.1016/j.jchemneu.2021.102043119117348082562-s2.0-85120177406Q4WOS:000731080400002Q3