Murali, RanjaniYıldız, Gökçe GülgezDaldal, FevziGennis, Robert B.2021-06-232021-06-2320120027-8424https://doi.org/10.1073/pnas.1207216109https://hdl.handle.net/20.500.12491/7151Recently, we reported (1) that the stoichiometry of proton pumping is about 0.4–0.5 proton per electron for members of the C family of respiratory oxygen reductases, also called the cbb3-type cytochrome c oxidases. This amount (0.5) is about half of the value obtained with the canonical A family of respiratory oxygen reductases, which includes the mitochondrial cytochrome c oxidases. We pointed out that the low stoichiometry correlates with the absence of the D channel for proton input and speculated that these properties may be an evolutionary adaptation to aerobic respiration under conditions of low oxygen.eninfo:eu-repo/semantics/openAccessRhodobacterStoichiometry of proton pumping by the cbb(3)-type oxygen reductase in whole cells of Rhodobacter capsulatus at pH 7 is about 0.5 H+ per electronLetter10.1073/pnas.120721610910932E2144E2144227613182-s2.0-84864655294Q1WOS:000307551700001Q1