Balbaba, MehmetUlaş, FatihPostacı, Sevinç ArzuÖz, BurakAydın, Süleyman2021-06-232021-06-2320200927-39481744-5078https://doi.org/10.1080/09273948.2019.1610461https://hdl.handle.net/20.500.12491/10711Purpose: To evaluate serum cortistatin (CST) levels in patients with ocular active and ocular inactive Behcet disease (BD) and its relationship with disease activity. Methods: 24 BD patients with ocular active, 24 BD patients with ocular inactive patients and 24 healthy control subjects were included in the study. Results: In ocular active and ocular inactive BD patients and healthy control subjects, the mean serum CST levels were 4.38 +/- 1.63ng/ml, 5.46 +/- 1.81ng/ml and 7.56 +/- 1.73ng/ml, respectively. ESR, serum CRP, CST levels and NLR were significantly different between the groups (p < 0.001 for all). The CST levels were similar between ocular active and inactive BD patient groups (p = 0.197). ESR, CRP and NLR were significantly higher in ocular active BD patients compared to ocular inactive BD patients and healthy control subjects (p < 0.05 for all). Conclusion: Serum CST level was significantly lower in BD patients. CST may be a neuropeptide that plays a role in the pathogenesis of BD.eninfo:eu-repo/semantics/closedAccessBehcet DiseaseBehcet Disease Ocular Attack Score 24CortistatinC-reactive ProteinErythrocyte Sedimentation RateNeutrophil-lymphocyte RatioArticle10.1080/09273948.2019.1610461284601605313146412-s2.0-85070287873Q1WOS:000476125200001Q2