Sağırlı, Akın2021-06-232021-06-2320200039-79111532-2432https://doi.org/10.1080/00397911.2020.1800742https://hdl.handle.net/20.500.12491/10370A facile synthesis of new pyrido[1,2-a]benzimidazoles through a one-pot multicomponent reaction of malononitrile, electron-deficient aryl aldehydes and heterocyclic enamines followed by a nitrous acid release under mild condition, is reported. Depending on the substituents on heterocyclic enamine, newly synthesized products have been obtained either as an inseparable mixture of regioisomers or as a single regioisomer. A plausible mechanism can be proposed for the formation of pyrido[1,2-a]benzimidazoles via this unfamiliar transformation with the HNO(2)extrusion. The structures of all title compounds were elucidated using spectroscopic methods and physical characteristics involving single crystal X-ray diffraction and TOF-MS measurements. In addition, among all the products, CN- and CF3-substituted ones showed promising absorption and fluorescent properties.eninfo:eu-repo/semantics/closedAccessHeterocyclic EnamineMulticomponent ReactionPyrido[1,2-a] BenzimidazoleArticle10.1080/00397911.2020.18007425021329833072-s2.0-85089252427Q3WOS:000557605600001Q3