Şengül, İbrahim FazılOkutan, ElifKandemir, HakanAstarcı, ErhanÇoşut, Bünyemin2021-06-232021-06-2320150143-72081873-3743https://doi.org/10.1016/j.dyepig.2015.07.025https://hdl.handle.net/20.500.12491/8128In this study, two different BODIPYs containing carbazole groups at the mesa position were designed and synthesized. All compounds were fully characterized by elemental analysis, FT-IR, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, H-1 and C-13 NMR spectroscopy. The photophysical properties of the new compounds were investigated by means of absorption and fluorescence spectroscopies in dilute dichloromethane solutions. We were also interested in the biological activity of these two novel carbazole-linked BODIPYs, particularly concerning their ability to inhibit human colon cancer HT29 cell lines. The photophysical studies revealed strong donor acceptor interaction between carbazole and BODIPY and follow the order compound 5 > compound 4. Also, preliminary assay showed that compound 5 possessed higher cytotoxic activity than compound 4, with IC50 values of 8.3 ng/mL and 21.7 ng/mL respectively. (C) 2015 Elsevier Ltd. All rights reserved.eninfo:eu-repo/semantics/closedAccessCarbazoleEnergy transferFluorescenceBiological ActivityBorondipyrromethenesLifetimeArticle10.1016/j.dyepig.2015.07.02512332382-s2.0-84938542442Q1WOS:000367768300005Q1