Sivri, NasirYalta, TülinYalta, KenanYetkin, ErtanAksoy, Yüksel2021-06-232021-06-2320110167-52731874-1754https://doi.org/10.1016/j.ijcard.2010.12.033https://hdl.handle.net/20.500.12491/6982The potential association between low bone mineral density (BMD) and coronary artery disease (CAD) has drawn particular attention in the recent years, but has yet remained to be thoroughly established. In their recently published article, Beer S. et al. investigated the association between low BMD and angiographically determined CAD in male patients [1]. The authors concluded that neither osteoporosis nor osteopenia is independently associated with the presence of CAD [1]. Likewise, in a previous study comprising postmenopausal women, neither CAD nor cardiovascular risk factors were found to be associated with low BMD [2]. However, as described below, low BMD may be closely associated with ectopic calcification in various tissues including heart valves, coronary arteries and atherosclerotic plaques etc. Extensive calcification of plaques associated with low BMD may particularly elicit propensity to a more stable plaque morphology possibly along with a reduced incidence of acute coronary syndromes (ACSs) in patients with established CAD and osteal pathologies.eninfo:eu-repo/semantics/closedAccessBone Mineral DensityAtherosclerotic Plaque MorphologyLetter10.1016/j.ijcard.2010.12.0331473448448211947592-s2.0-79952490381Q1WOS:000288168000026Q1