Dürüst, YaşarKarakuş, HamzaKariuki, Benson M.Knight, David W.2021-06-232021-06-2320180039-79111532-2432https://doi.org/10.1080/00397911.2018.1489966https://hdl.handle.net/20.500.12491/9716In situ generated 2,4-diaryl substituted munchnones from 2-(4-substitutedphenyl)-2-(N-methyl-N-4-substitutedbenzamido)acetic acids react with acetic anhydride in the presence of 2-nitromethylene thiazolidine, which is most likely acting as a base, and unexpectedly undergo a Dakin-West type reaction and a concurrent autoxidation reaction leading to the formation of (E)-1-(N,4-dimethylbenzamido)-1-(4-fluorophenyl)prop-1-en-2-yl acetate, 4-substitutedphenyl-N-methyl-N-(4-substitutedbenzoyl) benzamides and p-substituted benzoic acids. In addition, a novel and efficient access to N-acyl urea derivatives is described by the reaction between 2-(4-substitutedphenyl)-2-(N-methyl-N-4-substitutedbenzamido)acetic acids and cyclohexyl, isopropyl carbodiimides in the presence of a base. The structures of all new products were identified on the basis of NMR and IR spectra, along with X-ray diffraction data and HRMS measurements. [GRAPHICS] .eninfo:eu-repo/semantics/openAccessAcyl UreaDakin-West ReactionMunchnone PrecursorNitromethylene ThiazolidineArticle10.1080/00397911.2018.14899664817220622202-s2.0-85049630573Q3WOS:000443914600008Q3