Erkuş, EdipAktaş, GülaliKoçak, Mehmet ZahidDuman, Tuba TaslamacıoğluAtak, Burçin MeryemŞavlı, Haluk2021-06-232021-06-2320191806-9282https://doi.org/10.1590/1806-9282.65.1.51https://hdl.handle.net/20.500.12491/10215OBJECTIVE: Vitamin D deficiency is not only associated with bone metabolism but also with diabetes mellitus. We aimed to study the possible association between serum vitamin D concentration and HbA1c level in patients with type 2 diabetes mellitus (T2DM) in this retrospective report. METHODS: Patients with T2DM were enrolled to the study either in regulated or non-regulated T2DM groups, according to HbA1c levels. An HbA1c level of <8% was considered as relatively controlled and others were considered as poorly controlled T2DM. RESULTS: Serum vitamin D levels in poorly controlled T2DM subjects (9.4 (4.9-34) ng/ml) were significantly lower than that of the relatively well regulated T2DM patients (13.5 (3.4-36) ng/ml) (p=0.03). Vitamin D was strongly and inversely correlated with HbA1c levels (r= -0.295, p=0.005). CONCLUSION: Whatever the cause or result of the diabetes mellitus, it is clear that lower vitamin D is strongly associated with worse diabetic regulation in T2DM subjects. Randomized controlled larger studies, which research the relation between diabetic regulation and vitamin D status, are needed to claim whether it could be a therapeutic target in future in diabetic subjects.eninfo:eu-repo/semantics/openAccessVitamin DType 2 Diabetes MellitusGlycated Hemoglobin AArticle10.1590/1806-9282.65.1.516515155307584202-s2.0-85061482666N/AWOS:000458029400009Q4