The relationship of paraoxonase 1 activity with lipid metabolism in obese women
dc.authorid | 0000-0002-4060-3354 | |
dc.contributor.author | Özcan, Fatih | |
dc.contributor.author | Buğdaycı, Güler | |
dc.contributor.author | Serin, Erdinç | |
dc.contributor.author | Tosun, Mehmet | |
dc.date.accessioned | 2021-06-23T18:55:16Z | |
dc.date.available | 2021-06-23T18:55:16Z | |
dc.date.issued | 2014 | |
dc.department | BAİBÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü | en_US |
dc.description.abstract | Objective: The aim of this study was to identify the effects of serum lipids, apolipoprotein (apo) A-I, apo B and paraoxonase/arylesterase (PON1) activity on obesity in women. Methods: The study was conducted on 90 subjects categorized into three groups; there were 30 women in each group with an age range of 18-48 years. Group 1 had 30 abdominal obese patients, group 2 had 30 gynoid obeses and group 3 included 30 healthy control subjects. Results: There was a statistically significant difference between the triglyceride, high-density lipoprotein cholesterol (HDL-C), apo B, direct low-density lipoprotein cholesterol (D-LDL-C), high sensitive-CRP (hsCRP), homeostasis model insulin resistance (HOMA-IR) levels of group 1 and 2 (p=0.001, p<0.0001, p=0.016, p=0.001, p<0.0001, p<0.0001, respectively). For HDL-C, D-LDL-C, hsCRP and HOMA-IR levels, there were statistically significant differences between group 1 and 3 (p=0.023, p=0.023, p<0.0001, p=0.001, respectively). Triglyceride, apo B, HDL-C, D-LDL-C parameters differed significantly in abdominal obesity, whereas there was no difference among the groups for PON1 activity. Conclusion: Our results indicate that lipid metabolism is altered in obesity, but PON1 activity appears not to be affected. | en_US |
dc.identifier.doi | 10.12996/gmj.2014.03 | |
dc.identifier.endpage | 15 | en_US |
dc.identifier.issn | 2147-2092 | |
dc.identifier.issue | 1 | en_US |
dc.identifier.scopus | 2-s2.0-84940230851 | en_US |
dc.identifier.scopusquality | Q4 | en_US |
dc.identifier.startpage | 11 | en_US |
dc.identifier.uri | https://doi.org/10.12996/gmj.2014.03 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12491/4727 | |
dc.identifier.volume | 25 | en_US |
dc.identifier.wos | WOS:000217468400003 | en_US |
dc.identifier.wosquality | N/A | en_US |
dc.indekslendigikaynak | Web of Science | en_US |
dc.indekslendigikaynak | Scopus | en_US |
dc.institutionauthor | Buğdaycı, Güler | |
dc.institutionauthor | Tosun, Mehmet | |
dc.language.iso | en | en_US |
dc.publisher | Gazi Universitesi | en_US |
dc.relation.ispartof | Gazi Medical Journal | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Lipid Metabolism | en_US |
dc.subject | Obesity | en_US |
dc.subject | Paraoxonase 1 | en_US |
dc.title | The relationship of paraoxonase 1 activity with lipid metabolism in obese women | en_US |
dc.type | Article | en_US |
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