Effects of serum vitamin D level on ventricular repolarization in children and adolescents
Yükleniyor...
Dosyalar
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
AEPress SRO
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
OBJECTIVES: Low levels of vitamin D are known to increase cardiovascular mortality due to different risks. We aimed to examine whether low vitamin D levels in children and adolescents cause ventricular repolarization changes. METHODS: Sixtyseven healthy cases aged between 3.5 and 17 years were included. According to levels of vitamin D, cases were grouped as suffi cient (n=44), insuffi cient (n=13) and defi ciency (n=10). Ventricular repolarization parameters were measured manually. RESULTS: Levels of vitamin D were different for cases with insuffi ciency and defi ciency compared to suffi ciency ones (102 +/- 54.9 vs 24.4 +/- 7 ng/ml, p<0.001 and 102 +/- 54.9 vs 16.6 +/- 8.3 ng/ml, respectively, p<0.001). In the insuffi cient group the following parameters were different from suffi cient group: QTmean (357.8 +/- 25.3 vs 332 +/- 29.9 ms, p=0.012), JTc (310.8 +/- 20.2 vs 331.6 +/- 21 ms, p=0.005) and Tpe/QT (0.2 +/- 0.02 vs 0.22 +/- 0.02, p=0.02). It was found that the level of serum vitamin D correlated with JTc (r=-0.37, p=0.002), Tp-e (r=-0.29, p=0.015) and Tp-e/QT (r=-0.24, p=0.047). In the linear regression analysis, it was found that dropping level of vitamin D below normal was an independent risk factor for prolonged duration of JTc (p=0.015). CONCLUSIONS: Decline in vitamin D levels causes ventricular repolarization anomaly. As the decrease in vitamin D levels deepens, repolarization times become longer. These results could indicate that decrease in vitamin D levels can increase sensitivity to ventricular arrhythmias (Tab. 3, Ref. 45). Text in PDF www.elis.sk
Açıklama
This study was supported by the Research Fund of the Abant Izzet Baysal University, Turkey (Project no: 2019.08.01.1419) .
Anahtar Kelimeler
Adolescent, Arrhythmi, Child, Vitamin D, Ventricular Repolarization
Kaynak
Bratislava Medical Journal-Bratislavske Lekarske Listy
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
122
Sayı
11
Künye
Bekdas, M., Inanir, M., Ilhan, Z., & Ildes, E. (2021). Effects of serum vitamin D level on ventricular repolarization in children and adolescents. Bratislavske Lekarske Listy, 122(11), 816-820.
