Fragmented QRS May Be Associated with Subclinical Left Ventricular Dysfunction in Patients with Hypertension

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dc.contributor.authorKahyaoğlu, Muzaffer
dc.contributor.authorGeçmen, Çetin
dc.contributor.authorÇelik, Mehmet
dc.contributor.authorBayam, Emrah
dc.contributor.authorÇakmak, Ender Özgün
dc.contributor.authorKirma, Cevat
dc.contributor.authorYilmaz, Yusuf
dc.date.accessioned2024-09-25T20:23:47Z
dc.date.available2024-09-25T20:23:47Z
dc.date.issued2021
dc.departmentAbant İzzet Baysal Üniversitesien_US
dc.description.abstractIntroduction: In hypertensive patients, the early detection of subclinical left ventricular dysfunction could prevent or delay patients from heart failure by aggressive risk factor control and rigorous medical management. Fragmented QRS (fQRS) is a marker of myocardial fibrosis, and myocardial fibrosis causes left ventricular dysfunction in hypertensive patients. In this study, we aimed to assess the association between the presence of fQRS and LV function at hypertensive patients using the speckle tracking echocardiography method. Patients and Methods: The study included a total of 95 hypertensive patients. Detailed anamnesis, physical examination, laboratory tests, 12-lead electrocardiography, and conventional echocardiography were administered to all patients. The participating patients were divided into two groups as fQRS (+) (n= 33) and fQRS (-) (n= 62). Results: Compared to the fQRS (-) group, the fQRS (+) group had older age, the average duration of hypertension was longer, and had a higher hemoglobin level. In the fQRS (+) group, interventricular septum thickness, posterior wall thickness, left ventricular mass index, relative wall thickness, deceleration time, and E/Em were significantly higher while left ventricular global longitudinal strain values were lower compared to fQRS (-) group. In the multiple linear regression analysis, fQRS and duration of hypertension were identified as independent predictors of LV-GLS. Conclusion: In this study, we demonstrated that subclinical left ventricular dysfunction developing secondary to myocardial fibrosis could be predicted by fQRS, a simple marker in 12-lead electrocardiography..en_US
dc.identifier.doi10.51645/khj.2021.m67
dc.identifier.endpage119en_US
dc.identifier.issn2149-2980
dc.identifier.issue2en_US
dc.identifier.startpage114en_US
dc.identifier.trdizinid1117889en_US
dc.identifier.urihttps://doi.org/10.51645/khj.2021.m67
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1117889
dc.identifier.urihttps://hdl.handle.net/20.500.12491/16130
dc.identifier.volume24en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofKoşuyolu Heart Journalen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzYK_20240925en_US
dc.titleFragmented QRS May Be Associated with Subclinical Left Ventricular Dysfunction in Patients with Hypertensionen_US
dc.typeArticleen_US

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