Romatizmal hastalıklarda tiroid fonksiyonları
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Dosyalar
Tarih
2005
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Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Kas iskelet sistemi üzerine etkili en önemli hormonlardan birisi tiroid hormonudur. Tiroid fonksiyon bozukluklarının kas güçsüzlüğü, yorgunluk, osteopeni gibi romotolojik semptom ve bulgulara neden olduğu bilinmektedir. Bu sebeple, romatizmal hastalıkların ortaya çıkmasına tiroid fonksiyon bozukluklarının ne oranda katkıda bulunduğunu ve birlikteliklerini araştırmak istedik. Çalışmaya tek bir romatizmal hastalığı olan 873 hasta alındı. Osteoartrit olgularının % 1.01'inde subklinik hipotiroidi, % 3.03'ünde subklinik hipertiroidi, % 1.77'sinde hipertiroidi vardı. Osteoporoz olgularının % 2.5'inde subklinik hipotiroidi, % 11.95'inde subklinik hipertiroidi, % 2.17'sinde hipertiroidi saptandı. Yumuşak doku romatizmalı olguların % 0.8'inde subklinik hipotiroidi, % 5.3'ünde subklinik hipertiroidi ve disk hastalığı olan olguların da % 3.84'ünde subklinik hipertiroidi bulundu. FM olgularının % 2.08'inde (1) subklinik hipotiroidi, % 2.08'inde (1) TSH seviyesinde düşüklük saptandı. RA olgularının % 11.76'sında (2) TSH düzeyinde düşüklük saptanırken, AS hastalarında bu oran % 3.3 (1), KTS hastalarda ise % 7.6 (1) olarak gözlendi. Sistemik skleroz ve çakışma sendromlu 2 hastanın tiroid fonksiyon testlerinde herhangi bir bozukluk saptanmadı. Sonuç olarak; romatolojik hastalıklarla tiroid patolojileri çakışabilileceğinden romatizmal şikayetlerin kökenine inildiğinde tiroid patolojileri göz ardı edilmemeli ve uygun tedaviyle klinik sonuçların çok daha iyi olabileceği unutulmamalıdır.
Thyroid hormones are one of the most effective hormones on musculoskeletal system. It is well known that thyroid gland dysfunctions cause a variety of rheumatologic signs and symptoms including muscle weakness, fatigue and osteopenia. We aimed to evaluate the effects of thyroid function diseases on the occurrance of rheumatological diseases and coincidency of these two entities. 873 patients with rheumatological disorders were involved to the study. 1.01 % of patients with osteoarthritis had subclinical hypothyroidism, 3.03 % had subclinical hyperthyroidism, 1.77 % had clinical hyperthyroidism. 2.5 % of patients with osteoporosis had subclinical hypothyroidism, 11.95 % had subclinical hyperthyroidism, 2.17 % had clinical hyperthyroidism. 0.8 % of patients with soft tissue rheumatological diseases had subclinical hypothyroidism, 5.3 % had subclinical hyperthyroidism and 3.84 % of patiens with discus diseases had subclinical hyperthyroidism. 2.08 % of patients with fibromyalgia had subclinical hypothyroidism, 2.08 % of patients with fibromyalgia had subclinical hyperthyroidism. 11.76 % of patients with rheumatoid arthritis , 3.3 % of patients with ancylosing spondylitis, 7.6 % of patients with carpal-tunnel syndrome had subclinical hyperthyroidism. Two patients with syctemic sclerosis and overlap syndrome had normal thyroid functions. As a result, a variety of rheumatological and thyroid pathologies may overlap and thyroid diseases should always be in mind when evaluating rheumatological diseases. With proper combined treatment we can get better results.
Thyroid hormones are one of the most effective hormones on musculoskeletal system. It is well known that thyroid gland dysfunctions cause a variety of rheumatologic signs and symptoms including muscle weakness, fatigue and osteopenia. We aimed to evaluate the effects of thyroid function diseases on the occurrance of rheumatological diseases and coincidency of these two entities. 873 patients with rheumatological disorders were involved to the study. 1.01 % of patients with osteoarthritis had subclinical hypothyroidism, 3.03 % had subclinical hyperthyroidism, 1.77 % had clinical hyperthyroidism. 2.5 % of patients with osteoporosis had subclinical hypothyroidism, 11.95 % had subclinical hyperthyroidism, 2.17 % had clinical hyperthyroidism. 0.8 % of patients with soft tissue rheumatological diseases had subclinical hypothyroidism, 5.3 % had subclinical hyperthyroidism and 3.84 % of patiens with discus diseases had subclinical hyperthyroidism. 2.08 % of patients with fibromyalgia had subclinical hypothyroidism, 2.08 % of patients with fibromyalgia had subclinical hyperthyroidism. 11.76 % of patients with rheumatoid arthritis , 3.3 % of patients with ancylosing spondylitis, 7.6 % of patients with carpal-tunnel syndrome had subclinical hyperthyroidism. Two patients with syctemic sclerosis and overlap syndrome had normal thyroid functions. As a result, a variety of rheumatological and thyroid pathologies may overlap and thyroid diseases should always be in mind when evaluating rheumatological diseases. With proper combined treatment we can get better results.
Açıklama
Anahtar Kelimeler
Romatizmal Hastalıklar, Tiroid Fonksiyonları, Rheumatological Diseases, Thyroid Functions
Kaynak
Göztepe Tıp Dergisi
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
20
Sayı
4
