Evaluation of epicardial fat tissue thickness in patients with multiple sclerosis

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dc.contributor.authorCoşgun, Mehmet
dc.contributor.authorSincer, Isa
dc.contributor.authorYilmaz, Güneş Nurdan
dc.contributor.authorKök, Zafer
dc.contributor.authorTürkoğlu, Şule Aydin
dc.date.accessioned2024-09-25T20:18:25Z
dc.date.available2024-09-25T20:18:25Z
dc.date.issued2021
dc.departmentAbant İzzet Baysal Üniversitesien_US
dc.description.abstractAim: Multiple sclerosis (MS), which is inflammatory in its pathogenesis, damages the myelin sheath in the central nervous system (CNS) and causes axonal loss. Epicardial fat tissue (EFT), located between the myocardium and the visceral layer of the pericardium, surrounds the heart and several inflammatory cytokines is secreted from this tissue. In this study, we aimed to investigate EFT thickness in MS patients and compared with that of volunteer non-MS subjects. Methods: A total of 154 subjects comprising 61 MS patients and 93 volunteers matched for gender and age were included in our study. Epicardial fat tissue thickness was measured by echocardiography. All values were compared between groups.Results: Echocardiographic parameters were similar in both groups. However, the mean EFT thickness was significantly higher in the MS group than in the control group (p<0.001). Epicardial fat tissue thickness was also significantly correlated with the presence of MS (r=0.33, p<0.001). Conclusion: The results of our study suggest that the increase in epicardial adipose tissue thickness in MS patients may be a predictive factor for cardiovascular disease. However, the clinical significance of this finding and its relevance to MS pathogenesis should be investigated in further studies.en_US
dc.identifier.doi10.30714/j-ebr.2021165782
dc.identifier.endpage64en_US
dc.identifier.issn2618-6454
dc.identifier.issue1en_US
dc.identifier.startpage58en_US
dc.identifier.trdizinid417912en_US
dc.identifier.urihttps://doi.org/10.30714/j-ebr.2021165782
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/417912
dc.identifier.urihttps://hdl.handle.net/20.500.12491/15662
dc.identifier.volume4en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofExperimental Biomedical Researchen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzYK_20240925en_US
dc.titleEvaluation of epicardial fat tissue thickness in patients with multiple sclerosisen_US
dc.typeArticleen_US

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