A hidden danger in surgical neonatal intensive care units: Fungal sepsis
Küçük Resim Yok
Tarih
2004
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Background/aim: Nosocomial fungal sepsis has been increasingly recognized and is a highly mortal pathology in neonatal intensive care units. The most common causes of fungal sepsis are prolonged usage of wide spectrum antibiotics, prematurity, and low birth weight. There is limited data in the literature related to fungal sepsis in surgical neonatal intensive care units. The aim of this study is to evaluate the fungal sepsis in the surgical neonatal intensive care unit. Method: Patients treated in surgical intensive care unit. The between 1995 and 2001 were evaluated retrospectively with regard to mean age at admission, sex, weight, fungal sepsis, relation with bacterial sepsis, therapeutical approach, and mortality. Results: On average, 100.3 (87-124) cases per year are treated in our unit. Between 1995 and 2001 23 fungal sepsis cases diagnosed with a, the mean age at admission of 3.8 (1-14) days, the mean weight of 2376 g (1654-6400), and the male/female ratio was 17/6. Of these 23 cases of fungal sepsis, 17 had a concomitant bacterial sepsis. Bacterial agents were Enterobacter sp (n:11), MRSA (n:4), and others (n:2). The causative agent of all of the fungal sepsis was Candida albicans. The year in which the highest number of Candidal infections were seen was 1995 with a total number of 14, 8 of which were lost. With the prophylactic use of antifungal agent, cases of fungal sepsis decreased overtime and no case of fungal sepsis was detected in 2001. Conclusion: Prolonged hospitalization in intensive care units increase the incidence of nosocomial bacterial sepsis and therefore wide-spectum use of antibiotics increases the incidence of fungal sepsis. While prophylactic use of antifungal agents to prevent fungal sepsis seems to be a solution, it has additional risks. This necessitates strict hospital infection policies regulating antibiotic use.
Açıklama
Anahtar Kelimeler
Fungus, Intensive Care Unit, Mortality, Neonate, Sepsis
Kaynak
Pediatrik Cerrahi Dergisi
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
18
Sayı
1
