Comparison of chest x-ray, thoracic computed tomography and 18F-FDG PET/CT for staging of sarcoidosis
Küçük Resim Yok
Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
European Respiratory Soc Journals Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Sarcoidosis is an autoimmune disease that characterized by noncaseating granulomas with unknown etiology.Despite the highly advanced method for imaging, currently staging of sarcoidosis is performed by conventional chest X-ray. In this study we aimed to determine staging of sarcoidosis with chest X Ray and compare between thoracic computerized tomography and 18F-FDG PET/CT.43 patients with biopsy-proven sarcoidosis who underwent FDG-PET/CT during the initial work-up evaluated retrospectively.All cases, the chest X-Ray, thoracic CTand PET / CT scans were available and were studied approximately simultaneously.Staging of sarcoidosis was performed according to all three imaging.The Cohen's kappa was calculated to determine the rate of agreement.According to the Chest X-ray 3 patients in Stage 0, 27 in Stage 1,11 in Stage 2, 2 in Stage 3.Based on staging by Thoracic CT 9 in Stage 1,33 in Stage 2, one in Stage 3;staging with PET/CT,respectively,1 in Stage 0,16 in Stage 1,25 in Stage 2,one patient in Stage 3.The agreement was poor for considering staging between chest X-ray and thoracic CT (κ 0.128 35%), chest X-ray and PET/CT(κ 0.135 36%) and Thoracic CT and PET/ CT(κ 0.164 38%).The importance of advanced imaging methods such as CT and PET/CT is increasing for the determination of the activation and extend of the disease in patients with sarcoidosis. The management of sarcoidosis can be modified when this imaging methods used in staging.As a result, sarcoidosis staging and usage of these methods in appropriate patients can be discussed in the light of advanced imaging techniques for adequate management.
Açıklama
Anahtar Kelimeler
Sarcoidosis, Interstitial Lung Disease (connective tissue disease), Imaging
Kaynak
European Respiratory Journal
WoS Q Değeri
Q1
Scopus Q Değeri
Cilt
46
