A Novel Laboratory Marker for Hepatosteatosis:Mean Platelet Volume to Lymphocyte Count Ratio

Basit Öğe Kaydı
dc.contributor.authorBilgen, Satılmış
dc.contributor.authorKurtkulaği, Özge
dc.date.accessioned2024-09-25T20:23:35Z
dc.date.available2024-09-25T20:23:35Z
dc.date.issued2021
dc.departmentAbant İzzet Baysal Üniversitesien_US
dc.description.abstractAmaç: Hepatosteatosis (HS) is defined as accumulation of fat in liver reaching to an amount of at least 5% of liverweight. Not just mean platelet volume (MPV), but also MPV to lymphocyte ratio (MPVLR) has been introduced asa marker in inflammatory and metabolic conditions. We aimed to compare MPVLR values of patients with hepa tosteatosis with those of healthy controls. We also investigated the correlation between CRP and MPVLRMethods: The data of the patients with HS who were admitted to internal medicine outpatient clinics of our insti tution between 2018 December and 2019 December were enrolled into the study. The MPVLR were calculatedusing MPV/lymphocyte formula. Results: The median MPVLRs of the HS and control groups were 4.3% (2.1) and 3.6% (1.7), respectively (p<0.001).The median CRP levels of the HS and control groups were 3.6 (4.9) mg/L and 0.4 (0.2) mg/L, respectively (p<0.001).The MPVLR was positively and strongly correlated with CRP (r=0.64, p<0.001). However, MPVLR and the biochemi cal parameters; LDL-cholesterol, ALT and triglyceride were not correlated at all.. Conclusion: We suggest that elevated MPVLR should alert physicians for possible hepatosteatosis in a populationwithout comorbidities. Positive and strong correlation between CRP and MPVLR should also prompt use of MPVLRas a reliable inflammatory predictor.en_US
dc.identifier.doi10.5222/terh.2021.93798
dc.identifier.endpage83en_US
dc.identifier.issn1305-7073
dc.identifier.issn1305-7146
dc.identifier.issue1en_US
dc.identifier.startpage80en_US
dc.identifier.trdizinid463851en_US
dc.identifier.urihttps://doi.org/10.5222/terh.2021.93798
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/463851
dc.identifier.urihttps://hdl.handle.net/20.500.12491/15985
dc.identifier.volume31en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofİzmir Tepecik Eğitim Hastanesi Dergisien_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzYK_20240925en_US
dc.titleA Novel Laboratory Marker for Hepatosteatosis:Mean Platelet Volume to Lymphocyte Count Ratioen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu