In-vitro evaluation of the effects of tigecycline on annulus firosus and nucleus pulposus

Basit Öğe Kaydı
dc.contributor.authorKaya, Yasin Emre
dc.contributor.authorYılmaz, İbrahiM
dc.contributor.authorKaraarslan, Numan
dc.contributor.authorBilir, Bülent
dc.contributor.authorŞirin, Duygu Yaşar
dc.contributor.authorÖzbek, Hanefi
dc.date.accessioned2021-06-23T18:24:55Z
dc.date.available2021-06-23T18:24:55Z
dc.date.issued2020
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractAim: This study aimed to examine the effects of tigecycline on primary cell cultures established using intervertebral disc tissues. Material and Methods: Primary Annulus Fibrosus and Nucleus Pulposus cultures were obtained from human intervertebral disc tissue. Untreated samples served as the control group, and treated samples served as the study group. Treated and untreated samples were statistically evaluated using an alpha signifiance value of < 0.05. Results: Proliferation and gene expression decreased in the tigecycline administered cultures when compared to the control group samples (P < 0.05). Conclusion: Drugs used in clinics may have side effects other than those indicated in their package insert.en_US
dc.identifier.doi10.5455/annalsmedres.2020.03.224
dc.identifier.endpage1859en_US
dc.identifier.issn2636-7688
dc.identifier.issn2636-7688
dc.identifier.issue7en_US
dc.identifier.startpage1855en_US
dc.identifier.trdizinid370335en_US
dc.identifier.urihttps://doi.org/10.5455/annalsmedres.2020.03.224
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TXpjd016TTFOUT09
dc.identifier.urihttps://hdl.handle.net/20.500.12491/1027
dc.identifier.volume27en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorKaya, Yasin Emre
dc.language.isoenen_US
dc.relation.ispartofAnnals of Medical Researchen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subject[No Keywords]en_US
dc.titleIn-vitro evaluation of the effects of tigecycline on annulus firosus and nucleus pulposusen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu