Kolorektal kanserde lenf nodu oranı ve standart faktörlerin sağkalım ile ilişkisi
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Tarih
2013
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Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Kolorektal kanserli hastalarda, standart faktörlerin yanı sıra, tutulu lenf nodlarının çıkarılan lenf nodlarına oranının (LNR), sağkalımla olan ilişki- sinin belirlenmesi hedeflenmiştir. Yöntemler: Ocak 2003-Mart 2010 yılları arasında kolorektal kanser nedeniyle ameliyat edilen ve istenen kriterleri sağlayan 72 hastanın dosyaları, T, N ve M durumu ve evreleri, lenfovasküler ve perinöral invazyon varlığı, çıkarılan lenf nodu sayısı, tutulu lenf nodu sayısı, lenf nodu kapsül invazyonu varlığı ve LNR açısından incelenmiş ve bu parametrelerin sağkalımla ilişkileri retrospektif olarak araştırılmıştır. Bulgular: Kolorektal kanserli hastaların sağkalımlarıyla, LNR, lenf nodu evresi, tutulu lenf nodu sayısı, TNM evresi, PNI ve lenf nodu kapsül invazyonu varlığının korelasyon gösterdiği belirlenmiştir. Sonuç: LNR ve lenf nodu evresi, incelenen parametreler arasında sağkalımla en yüksek ilişkili parametreler olarak bulunmuştur.
Objective: The aim of our study is to investigate the relationship between overall survival and lymph node ratio (the number of positive lymph nodes divided by total number of lymph nodes) (LNR) as well as other standard prognostic factors in patients who underwent surgery for colorectal cancer. Methods: A retrospective study was performed to analyse the data collected for 72 patients who underwent surgery with the diagnosis of colorectal cancer from January 2003 to March 2010. The variables such as T, N and M stage, lymphovascular and perineural invasion, number of retrived lymph nodes, number of metastatic lymph nodes, lymph node capsule invasion, LNR and their effects on overall survival were analysed. Results: LNR, lymph node stage, number of metastatic lymph nodes, TNM stage, perineural invasion and lymph node capsule invasion had significant effects on overall survival. Conclusion: LNR and lymph node stage were the most significant variables associated with overall survival.
Objective: The aim of our study is to investigate the relationship between overall survival and lymph node ratio (the number of positive lymph nodes divided by total number of lymph nodes) (LNR) as well as other standard prognostic factors in patients who underwent surgery for colorectal cancer. Methods: A retrospective study was performed to analyse the data collected for 72 patients who underwent surgery with the diagnosis of colorectal cancer from January 2003 to March 2010. The variables such as T, N and M stage, lymphovascular and perineural invasion, number of retrived lymph nodes, number of metastatic lymph nodes, lymph node capsule invasion, LNR and their effects on overall survival were analysed. Results: LNR, lymph node stage, number of metastatic lymph nodes, TNM stage, perineural invasion and lymph node capsule invasion had significant effects on overall survival. Conclusion: LNR and lymph node stage were the most significant variables associated with overall survival.
Açıklama
Anahtar Kelimeler
Kolorektal Kanser, Lenf Nodu Oranı, Sağkalım, Prognoz, Colorectal Cancer, Lymph Node Ratio, Survival, Prognosis
Kaynak
JAREM
WoS Q Değeri
Scopus Q Değeri
Cilt
3
Sayı
1
