Breath-holding Spells: Etiological Factors, Laboratory Findings, and Rates of Response to Iron Therapy

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dc.contributor.authorHanci, Fatma
dc.contributor.authorTüray, Sevim
dc.contributor.authorTirink, Omer Faruk
dc.contributor.authorKabakuş, Nimet
dc.date.accessioned2024-09-25T20:15:28Z
dc.date.available2024-09-25T20:15:28Z
dc.date.issued2021
dc.departmentAbant İzzet Baysal Üniversitesien_US
dc.description.abstractAim: In this study, we aimed to investigate the etiological factors, electroencephalographic (EEG) findings, rates of response to iron therapy, and factors affecting response to iron therapy in children diagnosed with breath-holding spells (BHS). Methods: The study included 136 children aged 1 to 48 months who received iron therapy after a BHS diagnosis at our pediatric neurology clinic between November 2015 and No¬vember 2019. Patient medical records (physical examination, laboratory and EEG findings, medical history, and effectiveness of iron therapy) were reviewed retrospectively. Results: Of all patents, 81 (59.6%) exhibited partial response (partial remission) to iron therapy (50% decrease in BHS frequency), 52 (39%) responded completely (complete remission), and 2 were unresponsive. Comparison of the patients with complete and partial remission revealed a higher rate of complete remission in girls. In addition, patients with complete remission had higher levels of hemoglobin, MCV, and ferritin than those with partial remission. Complete remission rates were also higher in patients with normal EEG findings. Conclusion: BHS in childhood is a benign, recurring, and non-epileptic disorder and its differentiation from epilepsy is important. Children with BHS respond well to iron therapy, which can be recommended even if the serum iron and ferritin levels are normal.en_US
dc.identifier.doi10.21673/anadoluklin.797238
dc.identifier.endpage172en_US
dc.identifier.issn2149-5254
dc.identifier.issn2458-8849
dc.identifier.issue2en_US
dc.identifier.startpage165en_US
dc.identifier.trdizinid1151126en_US
dc.identifier.urihttps://doi.org/10.21673/anadoluklin.797238
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1151126
dc.identifier.urihttps://hdl.handle.net/20.500.12491/15179
dc.identifier.volume25en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofANADOLU KLİNİĞİ TIP BİLİMLERİ DERGİSİen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzYK_20240925en_US
dc.subjectBreath-holding spellsen_US
dc.subjectelectroencephalographyen_US
dc.subjectiron supplementationen_US
dc.titleBreath-holding Spells: Etiological Factors, Laboratory Findings, and Rates of Response to Iron Therapyen_US
dc.typeArticleen_US

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