Bisphenol A levels in bowel endometrioma diagnosed serums: A case control study
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Tarih
2022
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info:eu-repo/semantics/openAccess
Özet
Aim: To investigate the bisphenol A (BPA) levels, which may be a risk factor in the etiology of\rendometrioma, in patients diagnosed laparoscopically with endometrioma with and without bowel\rinvolvement.\rMethod: In the prospective cross-sectional case control study, 47 cases were included in the study, which were\radmitted to the gynecology and infertility services with and without bowel involvement endometrioma who\rwere operated and diagnosed histopathologically. 43 patients were included in the control group. For serum\rBPA value, blood samples taken immediately before the operation were studied in laboratory. Patients and\rcontrols were compared with controls in terms of serum BPA values.\rResults: The mean age of the patients was 35 ± 2 in the endometriosis group and 36 ± 2 in the control group\rwhich was and not statistically significant. There was no statistical difference between the patient and control\rgroups in terms of menstruation periods. Serum BPA levels were significantly higher in the bowel involvement\rgroup compared to the non-bowel involvement group, as the distribution width was higher due to excessive\rvalues, and only 5 patients with bowel involvement did not reach statistically significant levels. Serum BPA\rlevel was 1084±1132 ng/L in the endometriosis group and 269±99 ng/L in the control group which was\rstatistically significant (p<0,001).\rConclusions: BPA levels were showing very wide range especially in the patient group. Serum BPA levels\rwas statistically significantly higher in the endometrioma group compared to the control group. Therefore, in\rthe etiology of endometriosis BPA may take a definite place.
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Kaynak
Experimental Biomedical Research
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Cilt
5
Sayı
1
