Serum uric acid to HDL-cholesterol ratio could be promising predictor of atrioventricular nodal reentrant tachycardia

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dc.contributor.authorDonmez, Ibrahim
dc.contributor.authorCosgun, Mehmet
dc.contributor.authorBayraktar, Muhammed Fatih
dc.contributor.authorKorkmaz, Ufuk Turan Kursat
dc.contributor.authorDemirel, Mustafa Enes
dc.contributor.authorAcar, Emrah
dc.contributor.authorGunes, Yilmaz
dc.date.accessioned2024-09-25T20:16:49Z
dc.date.available2024-09-25T20:16:49Z
dc.date.issued2023
dc.departmentAbant İzzet Baysal Üniversitesien_US
dc.description.abstractAim: Paroxysmal supraventricular tachycardia (PSVT), particularly atrioventricular nodal reentrant tachycardia (AVNRT), is a common arrhythmia with no associated structural heart disease. Inflammation has been implicated in the pathogenesis of arrhythmias. Uric acid to high density lipoprotein (HDL)-cholesterol ratio (UHR) is a novel inflammation marker that has been investigated in various conditions. This study aimed to explore the potential association between UHR and AVNRT. Materials and Methods: A total of 136 patients were included in the study, including 86 patients with AVNRT and 50 controls with normal electrophysiological study. All patients’ medical records were reviewed, and data were obtained retrospectively. We recorded baseline features, hematologic and biochemical markers, and determined the UHR value. Results: UHR (p=0.031) and uric acid (p<0.001) levels were significantly higher, while HDL cholesterol (p=0.031) levels were significantly lower in the AVNRT group. Neutrophil leukocyte ratio (NLR) was also higher in the AVNRT group (p=0.034). However, in multivariate analysis, only UHR emerged as an independent predictor for AVNRT (OR: 1.088; 95%CI: 1.022 – 1.159; p=0.008). ROC curve analysis suggested a UHR cut-off > 14.05 for predicting AVNRT with 56% sensitivity and 76% specificity. Conclusion: This study identifies UHR as a promising predictor for AVNRT, shedding light on the potential role of inflammation in the arrhythmia’s development. Utilizing UHR as a readily accessible marker in the evaluation of AVNRT patients may have clinical implications.en_US
dc.identifier.doi10.5455/annalsmedres.2023.07.166
dc.identifier.endpage1045en_US
dc.identifier.issn2636-7688
dc.identifier.issue9en_US
dc.identifier.startpage1041en_US
dc.identifier.trdizinid1205174en_US
dc.identifier.urihttps://doi.org/10.5455/annalsmedres.2023.07.166
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1205174
dc.identifier.urihttps://hdl.handle.net/20.500.12491/15238
dc.identifier.volume30en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofAnnals of Medical Researchen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzYK_20240925en_US
dc.subjectArrhythmiaen_US
dc.subjectSupraventricular tachycardien_US
dc.subjectAVNRTen_US
dc.subjectUric acid/HDL ratioen_US
dc.titleSerum uric acid to HDL-cholesterol ratio could be promising predictor of atrioventricular nodal reentrant tachycardiaen_US
dc.typeArticleen_US

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