Does Mean Platelet Volume to Lymphocyte Ratio Associates with Irritable Bowel Syndrome and Its Subtypes?

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dc.contributor.authorDuman, Tuba Taslamacioğlu
dc.contributor.authorTel, Burçin Meryem Atak
dc.date.accessioned2024-09-25T20:23:46Z
dc.date.available2024-09-25T20:23:46Z
dc.date.issued2019
dc.departmentAbant İzzet Baysal Üniversitesien_US
dc.description.abstractINTRODUCTION: Hemogram parameters are considered as inflammatory markers in various diseases. The objective of this study was to assess mean platelet volume to lymphocyte ratio (MPVLR) of subjects with IBS and to compare to those in healthy population.METHODS: Patients with IBS whose admissions to our outpatient internal medicine clinic were enrolled to the study. Patients with IBS were divided into two groups according to the predominant symptom, either IBS diarrhea predominant (IBS-D) or IBS constipation predominant (IBS-C). Healthy volunteers were enrolled as control group. General characteristics and MPVLR levels of the groups compared.RESULTS: The MPVLR of IBS-C, IBS-D and control groups were 0.005 (0.001), 0.004 (0.001) and 0.003 (0.001), respectively (p<0.001). Post Hoc test revealed that MPVLR of IBS-C and IBS-D groups were similar (p=0.44) and MPVLR of control groups was significantly lower than that of the IBS-C (p<0.001) and IBS-D (p<0.001) groups.DISCUSSION and CONCLUSION: The main outcome of present study was that MPVLR could be used as a marker of IBS. However, it is not useful in differentiating IBS constipation predominance from IBS diarrhea predominance. In conclusion, despite increased MPVLR could not differentiate IBS constipation predominance from the IBS diarrheapredominance, it could be useful in establishing the diagnosis of IBS.en_US
dc.identifier.endpage54en_US
dc.identifier.issn2147-0758
dc.identifier.issue3en_US
dc.identifier.startpage50en_US
dc.identifier.trdizinid339153en_US
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/339153
dc.identifier.urihttps://hdl.handle.net/20.500.12491/16108
dc.identifier.volume8en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofKocaeli Tıp Dergisien_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzYK_20240925en_US
dc.titleDoes Mean Platelet Volume to Lymphocyte Ratio Associates with Irritable Bowel Syndrome and Its Subtypes?en_US
dc.typeArticleen_US

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