Synthesis of novel pyrrolo[3,2-c]carbazole and dipyrrolo[3,2-c: 2 ',3 '-g]carbazole derivatives
Yükleniyor...
Tarih
2016
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Georg Thieme Verlag Kg
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Pyrrolocarbazole and dipyrrolocarbazoles have been synthesized via the Hemetsberger indole synthesis, starting from 9-ethyl carbazole-3-carbaldehyde and 9-ethylcarbazole-3,6-dicarbaldeyde, respectively. The pyrrolocarbazole structures were confirmed through H-1 NMR, C-13 NMR, IR, mass spectrometry and single crystal X-ray diffraction techniques. The targeted compounds showed potent in vitro cytotoxicity against human colon cancer HT29 cells.
Açıklama
Anahtar Kelimeler
Carbazole, Pyrrolocarbazole, Hemetsberger Indolization, HT29 Cells, Cyctotoxicity
Kaynak
Synlett
WoS Q Değeri
Q2
Scopus Q Değeri
Q2
Cilt
27
Sayı
8
