Relationship between intracellular pathogens Toxoplasma gondii and Borreliaburgdorferi infections and migraine

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dc.contributor.authorYilmaz, Murat
dc.contributor.authorYilmaz, Ayşen Tuğba Canbaşoğlu
dc.contributor.authorTeker, Handan
dc.contributor.authorTürkoğlu, Şule Aydin
dc.contributor.authorYildiz, Serpil
dc.date.accessioned2024-09-25T20:18:28Z
dc.date.available2024-09-25T20:18:28Z
dc.date.issued2021
dc.departmentAbant İzzet Baysal Üniversitesien_US
dc.description.abstractAim: In this study, the serological values of our patients followed up with a diagnosis of migraine were compared with the results of healthy controls in terms of possible association with intracellular pathogens, Toxoplasma gondii and Borrelia burgdorferi. Methods: Fifty patients with migraine, randomly selected among migraine patients without any additional disease, who applied to Bolu Abant Izzet Baysal Training and Research Hospital between January 1, 2015 and August 31, 2019 were included in the study. Fifty subjects without headache were included as control group. The history of infectious diseases of the patient and control groups (Toxoplasma gondii, Borrelia burgdorferi- causing Lyme disease) was determined by serological diagnostic methods. Results: The study group consisted of 64 women with a mean age of 45.5±13.1 (15-76) years. Migraine and control groups were found to be similar in terms of age (p=0.059) and gender (p=0.211) distributions. The frequency of Toxoplasma gondii positivity in the migraine group was 28% (n=14) and 10% (n=5) in the control group. The frequency of Lyme was 19.6% (n=11) in the migraine group and 14.3% (n=8) in the control group. The frequency of Toxoplasma gondii positivity was statistically significantly higher in the migraine group (p=0.022), while the frequency of Lyme was found to be similar in the migraine and control groups (p=0.450). Conclusion: The results of our study suggest that there are statistically significant differences between migraine and control groups only in terms of Toxoplasma gondii positivity rates, not Lyme. However, we believe that larger sample studies are needed to determine the detailed relationship between migraine and Toxoplasma gondii infection.en_US
dc.identifier.doi10.30714/j-ebr.2021370082
dc.identifier.endpage236en_US
dc.identifier.issn2618-6454
dc.identifier.issue3en_US
dc.identifier.startpage230en_US
dc.identifier.trdizinid450289en_US
dc.identifier.urihttps://doi.org/10.30714/j-ebr.2021370082
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/450289
dc.identifier.urihttps://hdl.handle.net/20.500.12491/15672
dc.identifier.volume4en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofExperimental Biomedical Researchen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzYK_20240925en_US
dc.titleRelationship between intracellular pathogens Toxoplasma gondii and Borreliaburgdorferi infections and migraineen_US
dc.typeArticleen_US

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