The Association of Omentin Levels in Non-Diabetic Postmenopausal Women with Bone Mineral Density and Total Body Composition

dc.authorid0000-0003-2221-4731
dc.authorid0000-0002-3156-1076
dc.authorid0000-0002-9750-9350
dc.contributor.authorÖzlü, Tülay
dc.contributor.authorSarman, Hakan
dc.contributor.authorAlçelik, Aytekin
dc.contributor.authorIşık, Cengiz
dc.contributor.authorYazıcı, Selma
dc.contributor.authorTosun, Mehmet
dc.contributor.authorCaglar, Hilal
dc.date.accessioned2021-06-23T18:21:54Z
dc.date.available2021-06-23T18:21:54Z
dc.date.issued2015
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractObjectives: Positive relation between body mass and bone mineral density (BMD) is thought to be due to weight bearing effect. However, adipose tissue derived adipokines may have important effects on bone. Obese women have decreased levels of omentin in circulation which is related with adverse metabolic events. The hypothesis was that performed in this study, we aimed to study the association of omentin levels with body composition and BMD in non-diabetic postmenopausal women. Methods: Postmenopausal women aged 40 to 70 years, scheduled for BMD testing were prospectively evaluated. Patients with known diabetes, chronic renal failure, chronic liver disease, malabsorption, inflammatory bowel disease, <40 and >70 years of age were excluded. BMD and body composition were measured by DXA (GE-Lunar DPX pro). Fasting blood samples were obtained for analysis of complete blood count, glucose, creatinine, lipid profile and omentin. Statistical analyses were performed by using SPSS version 18 for windows. P<0.05 was considered statistically significant. Results: Mean age of the patients in the osteoporosis group was higher than that of the control group (59.1±7.6 vs 53.3±5.7, p<0.05). Mean omentin level was higher in osteoporosis group than in osteopenia and control groups (479.7±141.6 vs 342.3±173.6 and 346.8±127.2, p<0.05). Total body fat mass, muscle mass and the T score of lumbar spine had a negative correlation with omentin levels (r=-0.252, -0.276, -0.344, p<0.05). Conclusions: Body composition does not seem to effect omentin levels. Women with a lower BMI have increased omentin levels. Higher omentin levels are associated with lower T scores at the lumbar spine.en_US
dc.identifier.endpage57en_US
dc.identifier.issn2148-2357
dc.identifier.issn2148-2357
dc.identifier.issue2en_US
dc.identifier.startpage51en_US
dc.identifier.trdizinid192595en_US
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TVRreU5UazFOUT09
dc.identifier.urihttps://hdl.handle.net/20.500.12491/706
dc.identifier.volume3en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorÖzlü, Tülay
dc.institutionauthorSarman, Hakan
dc.institutionauthorAlçelik, Aytekin
dc.institutionauthorIşık, Cengiz
dc.institutionauthorYazıcı, Selma
dc.institutionauthorTosun, Mehmet
dc.institutionauthorÇağlar, Hilal
dc.language.isoenen_US
dc.relation.ispartofActa Medica Anatoliaen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGenel ve Dahili Tıpen_US
dc.titleThe Association of Omentin Levels in Non-Diabetic Postmenopausal Women with Bone Mineral Density and Total Body Compositionen_US
dc.typeArticleen_US

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