Does the use of dermojet affect the concentration of platelet-rich plasma? An in vitro experimental investigation
Yükleniyor...
Dosyalar
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
WILEY
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Needle-free injection systems with high jet pressure have been used for seven decades for drug or vaccine administration via intradermal, subcutaneous, and intramuscular routes. These systems are used for the application of mesotherapy drugs in plastic surgery and dermatology. Platelet-rich plasma (PRP) tissue regeneration is applied intradermally by a needle for different indications, such as wound healing and scar revision. To prevent complaints such as pain, erythema, and ecchymosis by patients during this application, PRP was applied using Dermojet, a jet injector system with a spring-loaded system. In this study, after measuring the average platelet count in PRP preparations obtained from 18 volunteers, a 2.5 cc PRP shot into an empty tube was performed with Dermojet. The mean platelet count was measured in a homogenized tube. The same procedures were performed for platelet-poor plasma (PPP). The platelet loss rates for PRP and PPP were compared. In addition, the amount of PRP in each shot of the Dermojet was calculated. When PRP and PPP were applied using the Dermojet, platelet loss was 8.41% and 8.33%, respectively. The difference in the number of platelets formed in PRP and PPP when applied with Dermojet was not statistically significant. PRP application with needle-free injection systems, such as Dermojet, may be an alternative because of patient comfort and the negligible platelet loss compared with the PRP application with the standard needle injection.
Açıklama
This project is supported by Scientific Research Projects unit of Abant Izzet Baysal University; (Project Number: BAP - 2016.08.18.1064).
Anahtar Kelimeler
Dermojet, In Vitro Experiment, Needle-Free Injection, Free Injection Technology, Free Jet Injection, Growth-Factors
Kaynak
Dermatologic Therapy
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
34
Sayı
4
Künye
Gökkaya, A., Görgü, M., Karanfil, E., & Acuner, B. (2021). Does the use of Dermojet affect the concentration of platelet‐rich plasma? An in vitro experimental investigation. Dermatologic Therapy, 34(4), e14996.
