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Öğe Paratesticular sarcomas: a report of seven cases(Spandidos Publ Ltd, 2015) Ünlü, Yaşar; Huq, Gülben Erdem; Özyalvaçlı, Gülzade; Zengin, Mehmet; Koca, Sevim BaykalPrimary tumors of the paratesticular region are rare, with paratesticular sarcomas constituting a major proportion of these tumors, particularly in the elderly. The paratesticular region consists of mesothelial, various epithelial and mesenchymal cells and may therefore give rise to a number of tumors with various behaviors. Defining the association between the paratesticular mass and the testicle, and differentiation between benign and malignant masses using radiology is challenging, therefore the mass is usually considered to be malignant and radical orchiectomy with high ligation is performed. The present study reports the cases of seven patients with tumors of the paratesticular region and presents the clinical and significant histological features of the tumors. In total, two patients suffered from dedifferentiated liposarcoma (DDLS), two exhibited leiomyosarcoma, two exhibited low-grade fibromyxoid sarcoma and one case of undifferentiated pleomorphic sarcoma was identified. Radical orchiectomy with high ligation was performed in five cases; simple orchiectomy was performed in one case and excisional biopsy was performed in the remaining case. A leiomyosarcomatous and epithelial membrane antigen (EMA) positive whorl pattern was observed during microscopy in the two DDLS cases. Additionally, one of the low-grade fibromyxoid sarcoma patients exhibited pleomorphism and mitosis in focal areas. To the best of our knowledge, the present study is the second time low-grade fibromyxoid sarcoma cases with paratesticular localization have been reported in the literature. Of the seven cases, four patients succumbed to the disease, one patient is living with the disorder and the two cases of DDLS are living without the disease. Paratesticular sarcomas are often aggressive and a multidisciplinary approach is required for the diagnosis and treatment of these tumors.Öğe A rare breast tumor; Adenomyoepithelioma: a case report and review of the literature(2022) Benek, Suat; Zengin, Mehmet; Baydar, Ahmet; Sevmiş, Murat; Gürler, MüjganAdenomyoepithelioma is rare benign breast neoplasia characterized by the proliferation of both epithelial and myoepithelial cells of the\rmammary lobules and ducts. This tumour, which does not have specific risk factors and radiological findings, is mostly seen in advanced\rages. This tumour, which occurs with the biphasic proliferation of epithelial and myoepithelial cells, also contains normal breast lobules and\rducts. This tumour is very difficult to diagnose and includes many radiological and pathological pitfalls. Although malignant degeneration\rhas been reported in the literature, it is a rare condition. In this study, we present a rare case with radiologically suspicious findings and\rpathologically reported as adenomyoepithelioma.