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    Effect of dipping status on QRS morphology in patients with hypertension
    (2010) Erden, Ismail; Erden, Emine Cakcak; Özhan, Hakan; Yalçin, Subhan; Basar, Cengiz; Aydin, Mesut
    BACKGROUND: Prolongation of the QRS complex on the surface electrocardiogram (ECG) has been shown to be predictive of cardiovascular outcomes in selected populations. A 'nondipper' blood pressure (BP) profile is currently regarded as a risk factor in its own right for cardiovascular events and target organ damage. The predictive value of ECG parameters in hypertensives with nondipper profile has not been established. MethodS: A total of 750 consecutive patients with hypertension who had been evaluated with ambulatory BP monitoring were screened for this study. One hundred and thirty-six patients who had fulfilled the inclusion and exclusion criteria were included in the final analysis. Dipper and nondipper patterns were detected and the maximum QRS duration (QRSd) measured on a 12-lead ECG was recorded. RESULTS: There were 70 nondipper and 66 dipper hypertensives. There was no significant difference between the two groups regarding the daytime systolic and diastolic mean BPs, number of medications taken, and the proportion of each class of antihypertensive medications. Other variables were similar between the two groups. QRSd was significantly higher in nondippers than dippers (P=0.006). Correlation analysis revealed that the systolic BP fall at night was inversely and significantly related with QRSd (r=-0.482, P<0.001). Regression analysis further showed that the systolic BP fall at night and age were independent correlates of QRSd. Conclusion: QRSd on the standard-surface 12-lead ECG was increased in patients with nondipper pattern and furthermore the systolic BP fall at night was independent correlate of QRSd in patients with hypertension. Copyright © 2010 Lippincott Williams & Wilkins.
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    Silent interrupted aortic arch in an elderly patient
    (Via Medica, 2011) Erden, Ismail; Kayapinar, Osman; Erden, Emine C.; Yalçin, Subhan
    Patients with complete interruption of the aortic arch (IAA) very rarely reach late adulthood without having undergone surgical intervention. Only a few cases of IAA in adults have beenne surgical intervention. Only a few cases of IAA in adults have been reported in the medical literature. In this case report, we present a late diagnosis of interrupted aortic arch in a 68 year-old male. Our patient was relatively asymptomatic until he presented with fatigue after walking quickly. A guidewire could not be passed to the aortic arch via the femoral approach; descending thoracic aortography revealed complete occlusion of the descending thoracic aorta. Cardiac catheterization via the right brachial artery confirmed the diagnosis of a complete interruption of the aortic arch distal to the left subclavian artery and showed distinct collateral circulation predominantly via the internal mammary arteries. Also, magnetic resonance angiography showed cuttings that reveal the interruption in the aortic arch and the prominent collateral vessels to the descending aorta. This case report was also interesting in that pressure measurements at a proximal point of the interrupted aortic arch were not hypertensive. Using both catheters, placed proximally and distally to the point of the interruption, by simultaneous pressure measurement, it was measured as 120/75 mm Hg at the proximal point, 60/40 mm Hg at the distal point. © 2011 Via Medica.